Body weight and the reward system: The volume of the right amygdala may be associated with body mass index in young overweight men

Gergely Orsi, Gabor Perlaki, N. Kovács, Mihaly Aradi, Zilia Papp, Kazmer Karadi, Csaba Szalay, Zoltan Karadi, L. Lénárd, T. Tényi, Eniko Plozer, R. Gábriel, Ferenc Nagy, T. Dóczi, S. Komoly, Hennric Jokeit, Attila Schwarcz, J. Janszky

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We aimed to investigate the relationship between BMI (body mass index) and the volumes of the structures of the reward system (hippocampus, amygdala, accumbens, caudatum, putamen, and orbitofrontal cortex). The right and left structures were examined separately. Their volumes were assessed using a 3-T MRI scanner and Freesurfer software. Ninety-two healthy subjects were involved (mean BMI: 22.3 ± 3.4 kg/m2, mean age: 23.2 ± 2.7). We found that the volume of the right amygdala positively correlated with the BMI in men but not in women. Moreover, we could demonstrate this association only in the overweight male sub-population. We suggest that an association between body weight and the morphological variability of the reward system can be demonstrated by MRI. This may be further evidence for a different body-weight regulation in the two sexes. The potential relationship between the volume of the right amygdala and the BMI in heavier individuals requires further studies with larger samples.

Original languageEnglish
Pages (from-to)149-157
Number of pages9
JournalBrain Imaging and Behavior
Volume5
Issue number2
DOIs
Publication statusPublished - Jun 2011

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Amygdala
Reward
Body Mass Index
Body Weight
Urodela
Putamen
Prefrontal Cortex
Hippocampus
Healthy Volunteers
Software
Population

Keywords

  • Amygdala
  • Freesurfer
  • Gender difference
  • Magnetic resonance volumetry
  • Obesity
  • Reward system

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Neurology
  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience
  • Behavioral Neuroscience
  • Radiology Nuclear Medicine and imaging

Cite this

Body weight and the reward system : The volume of the right amygdala may be associated with body mass index in young overweight men. / Orsi, Gergely; Perlaki, Gabor; Kovács, N.; Aradi, Mihaly; Papp, Zilia; Karadi, Kazmer; Szalay, Csaba; Karadi, Zoltan; Lénárd, L.; Tényi, T.; Plozer, Eniko; Gábriel, R.; Nagy, Ferenc; Dóczi, T.; Komoly, S.; Jokeit, Hennric; Schwarcz, Attila; Janszky, J.

In: Brain Imaging and Behavior, Vol. 5, No. 2, 06.2011, p. 149-157.

Research output: Contribution to journalArticle

Orsi, Gergely ; Perlaki, Gabor ; Kovács, N. ; Aradi, Mihaly ; Papp, Zilia ; Karadi, Kazmer ; Szalay, Csaba ; Karadi, Zoltan ; Lénárd, L. ; Tényi, T. ; Plozer, Eniko ; Gábriel, R. ; Nagy, Ferenc ; Dóczi, T. ; Komoly, S. ; Jokeit, Hennric ; Schwarcz, Attila ; Janszky, J. / Body weight and the reward system : The volume of the right amygdala may be associated with body mass index in young overweight men. In: Brain Imaging and Behavior. 2011 ; Vol. 5, No. 2. pp. 149-157.
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