Blood pressure control and response rates with zofenopril compared with amlodipine in hypertensive patients

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Angiotensin-converting enzyme inhibitors (ACEIs) and calcium antagonists are today extensively used as first-line monotherapy as well as appropriate combination therapy in mild to moderate hypertension. In a parallel-group study, using clinically recommended doses, the ACEI zofenopril was compared with the calcium antagonist amlodipine in respect of their antihypertensive properties. In the study, 303 hypertensive patients, aged 18-75 years, were compared in terms of antihypertensive response and adverse effects after treatment with zofenopril, 30-60 mg once daily or amlodipine 5-10 mg od. After receiving the lower starting dose, up-titration was optional at 4 weeks to the higher dose if diastolic pressure (DBP) was 90 mmHg or more or if a decrease from base line of

Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalBlood Pressure
Volume16
Issue numberSUPPL. 2
DOIs
Publication statusPublished - 2007

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zofenopril
Amlodipine
Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Blood Pressure
Calcium
Hypertension
Therapeutics

Keywords

  • amlodipine
  • Blood pressure control
  • response rate
  • zofenopril

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Blood pressure control and response rates with zofenopril compared with amlodipine in hypertensive patients. / Farsang, C.

In: Blood Pressure, Vol. 16, No. SUPPL. 2, 2007, p. 19-24.

Research output: Contribution to journalArticle

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