Blockade of thalamic GABAB receptors decreases EEG synchronization

G. Juhász, Z. Emri, K. Kékesi, Orsolya Salfay, Vincenzo Crunelli

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

The γ-aminobutyric acid (GABA)B receptor antagonists 2-OH-saclofen and CGP 35348 were injected in the thalamus of freely moving cats via a microdialysis probe while recording the sleep-waking cycle. The results obtained with the two antagonists were similar: wakefulness and the total sleep time were not affected by the blockade of GABAB receptors, but deep slow wave sleep and the mean power of slow waves (B receptors in the regulation of EEG slow waves.

Original languageEnglish
Pages (from-to)155-158
Number of pages4
JournalNeuroscience Letters
Volume172
Issue number1-2
DOIs
Publication statusPublished - May 19 1994

Fingerprint

Electroencephalography
Sleep
GABA-B Receptor Antagonists
Aminobutyrates
Wakefulness
Microdialysis
Thalamus
Cats
Power (Psychology)
CGP 35348
2-hydroxysaclofen
hydroxide ion

Keywords

  • EEG
  • GABA receptor
  • Oscillation
  • Sleep
  • Thalamus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Blockade of thalamic GABAB receptors decreases EEG synchronization. / Juhász, G.; Emri, Z.; Kékesi, K.; Salfay, Orsolya; Crunelli, Vincenzo.

In: Neuroscience Letters, Vol. 172, No. 1-2, 19.05.1994, p. 155-158.

Research output: Contribution to journalArticle

Juhász, G. ; Emri, Z. ; Kékesi, K. ; Salfay, Orsolya ; Crunelli, Vincenzo. / Blockade of thalamic GABAB receptors decreases EEG synchronization. In: Neuroscience Letters. 1994 ; Vol. 172, No. 1-2. pp. 155-158.
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