Blockade by cimetidine of the effects of histamine on adenylate cyclase activity, spontaneous rate and contractility in the developing praenatal heart

Mária Wollemann, J. Gy Papp

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The results support the view that in man cardiac responsiveness to histamine appears at a very early stage of development. It might also be suggested that in human embryonic and foetal hearts the adenylate cyclase activating, positive chronotropic and ventricular inotropic effects of histamine are mediated via H2-type histaminergic receptors.

Original languageEnglish
Pages (from-to)29-30
Number of pages2
JournalAgents and Actions
Volume9
Issue number1
DOIs
Publication statusPublished - Apr 1 1979

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology (medical)

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