Súlyos szívelégtelenség kezelése biventricularis ingerléssel.

Translated title of the contribution: Biventicular pacing in patients with severe heart failure

B. Merkely, H. Vágó, E. Bartha, E. Zima, E. Moravcsik, L. Gellér

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

According to initial clinical results biventricular pacing seems to be effective in the treatment of patients suffering from drug refractory severe heart failure combined with intraventricular conduction disturbance. Biventricular cardioverter defibrillators and biventricular pacemakers were implanted in patients suffering from drug refractory severe heart failure in 3 and in 2 cases, respectively (follow up > 6 months). NYHA III-IV functional class, low left ventricular ejection fraction (23.2 +/- 5.4%), wide QRS (> 150 ms) with left bundle branch block and lateral dyssynchrony were present in each case. The left ventricle was enlarged in each patient (end-diastolic/end-systolic diameter: 78.6 +/- 9.2/66.2 +/- 8.1 mm). The indications of cardioverter defibrillator implantations were both sustained ventricular tachycardia and ventricular fibrillation, nonsustained ventricular tachycardia combined with syncope in 2 and in 1 case, respectively. The duration of QRS decreased (190 +/- 36 vs. 134 +/- 17 ms, p = 0.012) and wall movement disorder disappeared. At the last follow up every patients were in NYHA II functional class and a decrease in left ventricular diameter could be observed (end-diastolic: 72 +/- 10.4 mm, p = 0.07; end-systolic: 62 +/- 10 mm, p = 0.09). During the follow up period (7.3 +/- 1.7 months) 18 episodes of ventricular arrhythmias could be detected in the same patient. Biventricular pacemakers and cardioverter defibrillators were implanted and applied successfully in the treatment of congestive heart failure for the first time in Hungary. The effect of biventricular pacing on morbidity and mortality, the cost-effectiveness, the exact indication and the combined use with cardioverter defibrillator have yet to be proven in future randomized trials.

Original languageHungarian
Pages (from-to)2835-2840
Number of pages6
JournalOrvosi Hetilap
Volume142
Issue number51
Publication statusPublished - Dec 23 2001

Fingerprint

Defibrillators
Heart Failure
Cardiac Resynchronization Therapy
Ventricular Tachycardia
Bundle-Branch Block
Hungary
Movement Disorders
Syncope
Ventricular Fibrillation
Pharmaceutical Preparations
Stroke Volume
Heart Ventricles
Cost-Benefit Analysis
Cardiac Arrhythmias
Morbidity
Mortality
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Súlyos szívelégtelenség kezelése biventricularis ingerléssel. / Merkely, B.; Vágó, H.; Bartha, E.; Zima, E.; Moravcsik, E.; Gellér, L.

In: Orvosi Hetilap, Vol. 142, No. 51, 23.12.2001, p. 2835-2840.

Research output: Contribution to journalArticle

Merkely, B, Vágó, H, Bartha, E, Zima, E, Moravcsik, E & Gellér, L 2001, 'Súlyos szívelégtelenség kezelése biventricularis ingerléssel.', Orvosi Hetilap, vol. 142, no. 51, pp. 2835-2840.
Merkely, B. ; Vágó, H. ; Bartha, E. ; Zima, E. ; Moravcsik, E. ; Gellér, L. / Súlyos szívelégtelenség kezelése biventricularis ingerléssel. In: Orvosi Hetilap. 2001 ; Vol. 142, No. 51. pp. 2835-2840.
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