Birth Outcomes of Children Born to Women with Rheumatoid Arthritis

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

AIM: The aim of the study was to estimate the possible risk of adverse birth outcomes of children born to mothers with rheumatoid arthritis (RA).

METHODS: The dataset of large population-based Hungarian Case-Control Surveillance System of Congenital Abnormalities from 1980-1996 was evaluated including 22,843 cases with congenital abnormalities and 38,151 matched controls without any defect.

RESULTS: 36 cases (0.16%) had mothers with RA, while 68 controls (0.18%) were born to mothers without RA (OR=0.9, 95% CI=0.3-1.6). A higher risk for congenital abnormalities in the offspring of pregnant women with RA was not found. In fact there was a larger mean birth weight in the newborns without any defect of mothers with RA and it was associated with a somewhat lower rate of low birth weight.

CONCLUSIONS: RA seems to have a beneficial effect not only for pregnant women but for their foetuses as well.

Original languageEnglish
Pages (from-to)104-110
Number of pages7
JournalCentral European Journal of Public Health
Volume23
Issue number2
Publication statusPublished - Jun 1 2015

Fingerprint

Rheumatoid Arthritis
Parturition
Mothers
Pregnant Women
Low Birth Weight Infant
Birth Weight
Fetus
Newborn Infant
Population

Keywords

  • birth weight
  • congenital abnormalities
  • population-based case-control study
  • pregnancy
  • preterm birth
  • rheumatoid arthritis

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Birth Outcomes of Children Born to Women with Rheumatoid Arthritis. / Pósfai, Éva; Bánhidy, F.; Urbán, R.; Czeizel, E.

In: Central European Journal of Public Health, Vol. 23, No. 2, 01.06.2015, p. 104-110.

Research output: Contribution to journalArticle

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N2 - AIM: The aim of the study was to estimate the possible risk of adverse birth outcomes of children born to mothers with rheumatoid arthritis (RA).METHODS: The dataset of large population-based Hungarian Case-Control Surveillance System of Congenital Abnormalities from 1980-1996 was evaluated including 22,843 cases with congenital abnormalities and 38,151 matched controls without any defect.RESULTS: 36 cases (0.16%) had mothers with RA, while 68 controls (0.18%) were born to mothers without RA (OR=0.9, 95% CI=0.3-1.6). A higher risk for congenital abnormalities in the offspring of pregnant women with RA was not found. In fact there was a larger mean birth weight in the newborns without any defect of mothers with RA and it was associated with a somewhat lower rate of low birth weight.CONCLUSIONS: RA seems to have a beneficial effect not only for pregnant women but for their foetuses as well.

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