Birth outcome in Danish women with cutaneous malignant melanoma

Vivian Langagergaard, E. Puhó, Timothy L. Lash, Bente Nørgård, Henrik T. Sørensen

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Several factors may affect birth outcome in women with cutaneous malignant melanoma. We examined whether maternal cutaneous malignant melanoma affects birth outcome (preterm birth, low birth weight at term, stillbirth, congenital abnormalities, mean birth weight, and male proportion of newborns) in a nationwide cohort study of 1059 births from 1973 to 2002 to women with cutaneous melanoma, compared with 50 794 births from a cohort of mothers without cancer. We found no increased risk of adverse birth outcome for the 620 newborns born to women with a diagnosis of melanoma before pregnancy or the 88 newborns born to women diagnosed during pregnancy. Among 351 births of women diagnosed with melanoma within 2 years from the time of delivery, the prevalence odds ratio of stillbirth was 4.6 (95% confidence interval: 1.7; 12). This estimate was, however, based on only five stillbirths in the exposed group and was an unexpected finding. With this exception, our data suggest no substantially increased risk of adverse birth outcome for women with melanoma.

Original languageEnglish
Pages (from-to)31-36
Number of pages6
JournalMelanoma Research
Volume17
Issue number1
DOIs
Publication statusPublished - Feb 2007

Fingerprint

Parturition
Stillbirth
Melanoma
Newborn Infant
Mothers
Pregnancy
Premature Birth
Low Birth Weight Infant
Cutaneous Malignant Melanoma
Birth Weight
Cohort Studies
Odds Ratio
Confidence Intervals
Skin
Neoplasms

Keywords

  • Birth outcome
  • Cohort study
  • Epidemiology
  • Melanoma

ASJC Scopus subject areas

  • Cancer Research
  • Dermatology

Cite this

Langagergaard, V., Puhó, E., Lash, T. L., Nørgård, B., & Sørensen, H. T. (2007). Birth outcome in Danish women with cutaneous malignant melanoma. Melanoma Research, 17(1), 31-36. https://doi.org/10.1097/CMR.0b013e3280124749

Birth outcome in Danish women with cutaneous malignant melanoma. / Langagergaard, Vivian; Puhó, E.; Lash, Timothy L.; Nørgård, Bente; Sørensen, Henrik T.

In: Melanoma Research, Vol. 17, No. 1, 02.2007, p. 31-36.

Research output: Contribution to journalArticle

Langagergaard, V, Puhó, E, Lash, TL, Nørgård, B & Sørensen, HT 2007, 'Birth outcome in Danish women with cutaneous malignant melanoma', Melanoma Research, vol. 17, no. 1, pp. 31-36. https://doi.org/10.1097/CMR.0b013e3280124749
Langagergaard, Vivian ; Puhó, E. ; Lash, Timothy L. ; Nørgård, Bente ; Sørensen, Henrik T. / Birth outcome in Danish women with cutaneous malignant melanoma. In: Melanoma Research. 2007 ; Vol. 17, No. 1. pp. 31-36.
@article{f88472ff67b84237bd7996d4fa9561e9,
title = "Birth outcome in Danish women with cutaneous malignant melanoma",
abstract = "Several factors may affect birth outcome in women with cutaneous malignant melanoma. We examined whether maternal cutaneous malignant melanoma affects birth outcome (preterm birth, low birth weight at term, stillbirth, congenital abnormalities, mean birth weight, and male proportion of newborns) in a nationwide cohort study of 1059 births from 1973 to 2002 to women with cutaneous melanoma, compared with 50 794 births from a cohort of mothers without cancer. We found no increased risk of adverse birth outcome for the 620 newborns born to women with a diagnosis of melanoma before pregnancy or the 88 newborns born to women diagnosed during pregnancy. Among 351 births of women diagnosed with melanoma within 2 years from the time of delivery, the prevalence odds ratio of stillbirth was 4.6 (95{\%} confidence interval: 1.7; 12). This estimate was, however, based on only five stillbirths in the exposed group and was an unexpected finding. With this exception, our data suggest no substantially increased risk of adverse birth outcome for women with melanoma.",
keywords = "Birth outcome, Cohort study, Epidemiology, Melanoma",
author = "Vivian Langagergaard and E. Puh{\'o} and Lash, {Timothy L.} and Bente N{\o}rg{\aa}rd and S{\o}rensen, {Henrik T.}",
year = "2007",
month = "2",
doi = "10.1097/CMR.0b013e3280124749",
language = "English",
volume = "17",
pages = "31--36",
journal = "Melanoma Research",
issn = "0960-8931",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Birth outcome in Danish women with cutaneous malignant melanoma

AU - Langagergaard, Vivian

AU - Puhó, E.

AU - Lash, Timothy L.

AU - Nørgård, Bente

AU - Sørensen, Henrik T.

PY - 2007/2

Y1 - 2007/2

N2 - Several factors may affect birth outcome in women with cutaneous malignant melanoma. We examined whether maternal cutaneous malignant melanoma affects birth outcome (preterm birth, low birth weight at term, stillbirth, congenital abnormalities, mean birth weight, and male proportion of newborns) in a nationwide cohort study of 1059 births from 1973 to 2002 to women with cutaneous melanoma, compared with 50 794 births from a cohort of mothers without cancer. We found no increased risk of adverse birth outcome for the 620 newborns born to women with a diagnosis of melanoma before pregnancy or the 88 newborns born to women diagnosed during pregnancy. Among 351 births of women diagnosed with melanoma within 2 years from the time of delivery, the prevalence odds ratio of stillbirth was 4.6 (95% confidence interval: 1.7; 12). This estimate was, however, based on only five stillbirths in the exposed group and was an unexpected finding. With this exception, our data suggest no substantially increased risk of adverse birth outcome for women with melanoma.

AB - Several factors may affect birth outcome in women with cutaneous malignant melanoma. We examined whether maternal cutaneous malignant melanoma affects birth outcome (preterm birth, low birth weight at term, stillbirth, congenital abnormalities, mean birth weight, and male proportion of newborns) in a nationwide cohort study of 1059 births from 1973 to 2002 to women with cutaneous melanoma, compared with 50 794 births from a cohort of mothers without cancer. We found no increased risk of adverse birth outcome for the 620 newborns born to women with a diagnosis of melanoma before pregnancy or the 88 newborns born to women diagnosed during pregnancy. Among 351 births of women diagnosed with melanoma within 2 years from the time of delivery, the prevalence odds ratio of stillbirth was 4.6 (95% confidence interval: 1.7; 12). This estimate was, however, based on only five stillbirths in the exposed group and was an unexpected finding. With this exception, our data suggest no substantially increased risk of adverse birth outcome for women with melanoma.

KW - Birth outcome

KW - Cohort study

KW - Epidemiology

KW - Melanoma

UR - http://www.scopus.com/inward/record.url?scp=33846437509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846437509&partnerID=8YFLogxK

U2 - 10.1097/CMR.0b013e3280124749

DO - 10.1097/CMR.0b013e3280124749

M3 - Article

C2 - 17235239

AN - SCOPUS:33846437509

VL - 17

SP - 31

EP - 36

JO - Melanoma Research

JF - Melanoma Research

SN - 0960-8931

IS - 1

ER -