Biospeciation of insulin-mimetic VO(IV) complexes

T. Kiss, T. Jakusch, Dominik Hollender, Agnes Dörnyei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

17 Citations (Scopus)

Abstract

The possible transformation reactions of several insulinmimetic vanadium(IV) complexes taking place in the organism after oral administration are discussed in the chapter. These reactions involve the (i) absorption processes in the gastrointestinal tract, (ii) their transport in the blood stream and (iii) interactions with endogenous binding molecules in the glucose metabolizing cells. Modeling studies are used mostly to determine the actual chemical form of the vanadium(IV) complexes in the various biological environments. In some cases in vitro and in vivo biological results confirm the basic findings obtained by the modeling.

Original languageEnglish
Title of host publicationACS Symposium Series
Pages323-339
Number of pages17
Volume974
Publication statusPublished - 2007

Publication series

NameACS Symposium Series
Volume974
ISSN (Print)00976156

Fingerprint

Vanadium
Insulin
Blood
Glucose
Molecules

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Kiss, T., Jakusch, T., Hollender, D., & Dörnyei, A. (2007). Biospeciation of insulin-mimetic VO(IV) complexes. In ACS Symposium Series (Vol. 974, pp. 323-339). (ACS Symposium Series; Vol. 974).

Biospeciation of insulin-mimetic VO(IV) complexes. / Kiss, T.; Jakusch, T.; Hollender, Dominik; Dörnyei, Agnes.

ACS Symposium Series. Vol. 974 2007. p. 323-339 (ACS Symposium Series; Vol. 974).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kiss, T, Jakusch, T, Hollender, D & Dörnyei, A 2007, Biospeciation of insulin-mimetic VO(IV) complexes. in ACS Symposium Series. vol. 974, ACS Symposium Series, vol. 974, pp. 323-339.
Kiss T, Jakusch T, Hollender D, Dörnyei A. Biospeciation of insulin-mimetic VO(IV) complexes. In ACS Symposium Series. Vol. 974. 2007. p. 323-339. (ACS Symposium Series).
Kiss, T. ; Jakusch, T. ; Hollender, Dominik ; Dörnyei, Agnes. / Biospeciation of insulin-mimetic VO(IV) complexes. ACS Symposium Series. Vol. 974 2007. pp. 323-339 (ACS Symposium Series).
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