Biologically relevant small radicals

Georg Bauer, Chryssostomos Chatgilialoglu, Jerzy L. Gebicki, Lidia Gebicka, Georg Gescheidt, Bernard T. Golding, Sara Goldstein, Jozsef Kaizer, Gabor Merenyi, Gabor Speien, Peter Wardman

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Biologically relevant small radicals are at the focus of the working group 4 (WG4) of the COST Action CM0603 (Free Radicals in Chemical Biology, CHEMBIORADICAL). This article surveys the areas of research being undertaken by the partners in WG4. The character of the radicals is described together with experimental techniques utilized to follow their structure and reactivity. Specifically, C-, S-, N- and O-centered radicals of small size, and their interaction with different biomolecules are described. Processes at the molecular level exemplifying important biological signaling and damaging pathways are introduced.

Original languageEnglish
Pages (from-to)704-712
Number of pages9
JournalChimia
Volume62
Issue number9
DOIs
Publication statusPublished - Oct 22 2008

Keywords

  • Antioxidants
  • Reactive carbon species
  • Reactive nitrogen species
  • Reactive oxygen species
  • Reactive sulfur species
  • Signaling pathways

ASJC Scopus subject areas

  • Chemistry(all)

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  • Cite this

    Bauer, G., Chatgilialoglu, C., Gebicki, J. L., Gebicka, L., Gescheidt, G., Golding, B. T., Goldstein, S., Kaizer, J., Merenyi, G., Speien, G., & Wardman, P. (2008). Biologically relevant small radicals. Chimia, 62(9), 704-712. https://doi.org/10.2533/chimia.2008.704