Biologically active compounds of Helichrysum arenarium (L.) Moench

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17 Citations (Scopus)

Abstract

The biologically important components of Helichrysum arenarium (L.) Moench are the flavonoids, which may have choleretic, hepatoprotective and antimicrobial properties. During our study, we examined the flavonoids present in the lyophilizate of the inflorescence of Helichrysum arenarium (L.) Moench (Helichrysi flos, syn. Stoechados flos) and in the tea made from the inflorescence via qualitative and quantitative analysis, and determined the flavonoid content. We examined the properties of the lyophilizate antioxidant, and measured the H-donor activity, reducing power property and total scavenger-capacity via spectrophotometric and chemiluminescent methods. We compared the results with those of the agent present in milk thistle (Silybum marianum L.), the silibinin flavonoid. Regarding the H-donor activity, our lyophilizate was determined to be more effective than the silibinin at the same amounts; on the other hand, its reducing power property and total scavenger capacity was lower than that of silibinin. The flavonoid content, which is responsible for the lyophilizate effect, was found to be 0.47% according to our measurements; it is, therefore, possible that an extract with such a concentration of flavonoids may be of therapeutic benefit.

Original languageEnglish
Pages (from-to)309-313
Number of pages5
JournalEuropean Journal of Drug Metabolism and Pharmacokinetics
Volume24
Issue number4
Publication statusPublished - 1999

Fingerprint

Helichrysum
Flavonoids
Milk Thistle
Inflorescence
Cholagogues and Choleretics
Tea
Antioxidants

Keywords

  • Antioxidant activity
  • Asteraceae
  • Flavonoid content
  • Helichrysum arenarium (L.) Moench
  • Stoechados flos

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

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title = "Biologically active compounds of Helichrysum arenarium (L.) Moench",
abstract = "The biologically important components of Helichrysum arenarium (L.) Moench are the flavonoids, which may have choleretic, hepatoprotective and antimicrobial properties. During our study, we examined the flavonoids present in the lyophilizate of the inflorescence of Helichrysum arenarium (L.) Moench (Helichrysi flos, syn. Stoechados flos) and in the tea made from the inflorescence via qualitative and quantitative analysis, and determined the flavonoid content. We examined the properties of the lyophilizate antioxidant, and measured the H-donor activity, reducing power property and total scavenger-capacity via spectrophotometric and chemiluminescent methods. We compared the results with those of the agent present in milk thistle (Silybum marianum L.), the silibinin flavonoid. Regarding the H-donor activity, our lyophilizate was determined to be more effective than the silibinin at the same amounts; on the other hand, its reducing power property and total scavenger capacity was lower than that of silibinin. The flavonoid content, which is responsible for the lyophilizate effect, was found to be 0.47{\%} according to our measurements; it is, therefore, possible that an extract with such a concentration of flavonoids may be of therapeutic benefit.",
keywords = "Antioxidant activity, Asteraceae, Flavonoid content, Helichrysum arenarium (L.) Moench, Stoechados flos",
author = "E. Czinner and A. K{\'e}ry and K. Hagym{\'a}si and A. Bl{\'a}zovics and A. Lugasi and E. Szőke and E. Lemberkovics",
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T1 - Biologically active compounds of Helichrysum arenarium (L.) Moench

AU - Czinner, E.

AU - Kéry, A.

AU - Hagymási, K.

AU - Blázovics, A.

AU - Lugasi, A.

AU - Szőke, E.

AU - Lemberkovics, E.

PY - 1999

Y1 - 1999

N2 - The biologically important components of Helichrysum arenarium (L.) Moench are the flavonoids, which may have choleretic, hepatoprotective and antimicrobial properties. During our study, we examined the flavonoids present in the lyophilizate of the inflorescence of Helichrysum arenarium (L.) Moench (Helichrysi flos, syn. Stoechados flos) and in the tea made from the inflorescence via qualitative and quantitative analysis, and determined the flavonoid content. We examined the properties of the lyophilizate antioxidant, and measured the H-donor activity, reducing power property and total scavenger-capacity via spectrophotometric and chemiluminescent methods. We compared the results with those of the agent present in milk thistle (Silybum marianum L.), the silibinin flavonoid. Regarding the H-donor activity, our lyophilizate was determined to be more effective than the silibinin at the same amounts; on the other hand, its reducing power property and total scavenger capacity was lower than that of silibinin. The flavonoid content, which is responsible for the lyophilizate effect, was found to be 0.47% according to our measurements; it is, therefore, possible that an extract with such a concentration of flavonoids may be of therapeutic benefit.

AB - The biologically important components of Helichrysum arenarium (L.) Moench are the flavonoids, which may have choleretic, hepatoprotective and antimicrobial properties. During our study, we examined the flavonoids present in the lyophilizate of the inflorescence of Helichrysum arenarium (L.) Moench (Helichrysi flos, syn. Stoechados flos) and in the tea made from the inflorescence via qualitative and quantitative analysis, and determined the flavonoid content. We examined the properties of the lyophilizate antioxidant, and measured the H-donor activity, reducing power property and total scavenger-capacity via spectrophotometric and chemiluminescent methods. We compared the results with those of the agent present in milk thistle (Silybum marianum L.), the silibinin flavonoid. Regarding the H-donor activity, our lyophilizate was determined to be more effective than the silibinin at the same amounts; on the other hand, its reducing power property and total scavenger capacity was lower than that of silibinin. The flavonoid content, which is responsible for the lyophilizate effect, was found to be 0.47% according to our measurements; it is, therefore, possible that an extract with such a concentration of flavonoids may be of therapeutic benefit.

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KW - Flavonoid content

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KW - Stoechados flos

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