Biological activity of precocene analogues on Locusta migratoria

I. Kiss, A. Fodor, T. Timar, S. Hosztafi, P. Sebok, T. Torok, E. Viragh, M. Berenyi

Research output: Contribution to journalArticle

18 Citations (Scopus)


Structure-optimization studies of C-5-C-8-substituted precocene (P) analogues revealed that 1) compounds disubstituted asymmetrically at C-6, C-7 had an anti-allatal effect only if the C-6 side-group was shorter than that at C-7, 2) in the case of C-5, C-7 disubstitution, activity was enhanced by Me at C-5 whereas MeO caused inactivity. Effects of various other substitutions are also discussed.

Original languageEnglish
Pages (from-to)790-792
Number of pages3
Issue number9
Publication statusPublished - Sep 1 1988


  • Locusta migratoria
  • Precocene
  • effect of C-5-C-8 substitution and their combination
  • structure-activity relationship

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Kiss, I., Fodor, A., Timar, T., Hosztafi, S., Sebok, P., Torok, T., Viragh, E., & Berenyi, M. (1988). Biological activity of precocene analogues on Locusta migratoria. Experientia, 44(9), 790-792.