Biological activity of Feijoa peel extracts

N. Motohashi, M. Kawase, Y. Shirataki, S. Tani, S. Saito, H. Sakagami, T. Kurihara, H. Nakashima, K. Wolfard, I. Mucsi, A. Varga, J. Molnár

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33 Citations (Scopus)

Abstract

Fractionated extracts of Feijoa peels were studied for cytotoxic activity, anti-human immunodeficiency virus (HIV) activity and antibacterial activity. Two most cytotoxic fractions A3 of acetone extract and M2 of methanol extract had potent inhibitory activity against Gram-positive and Gram-negative bacteria as well as fungi tested. Fraction A4 of acetone extract showed multidrug resistance (MDR)-reversal activity comparable with that of verapamil (positive control). These results indicate the therapeutic value of Feijoa peel extracts as potential antimicrobial and MDR-modulating agents.

Original languageEnglish
Pages (from-to)4323-4329
Number of pages7
JournalAnticancer research
Volume20
Issue number6 B
Publication statusPublished - Dec 1 2000

Keywords

  • Anti-bacterial
  • Extract cytotoxic activity
  • Feijoa sellowiana
  • MDR
  • Peel

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Motohashi, N., Kawase, M., Shirataki, Y., Tani, S., Saito, S., Sakagami, H., Kurihara, T., Nakashima, H., Wolfard, K., Mucsi, I., Varga, A., & Molnár, J. (2000). Biological activity of Feijoa peel extracts. Anticancer research, 20(6 B), 4323-4329.