Plantago media L antitumor hatoanyagainak szerkezete es biologiai aktivitasa

Translated title of the contribution: Biological activity and structure of antitumor compounds from Plantago media L.

Mónika Kunvári, Csilla Páska, Miklós László, L. Őrfi, István Kövesdi, Dániel Eros, Gyöngyi Bökönyi, G. Kéri, István Gyurján

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Tyrosine kinase inhibition and tumor growth inhibition activity of verbascoside and homoplantaginin are described. Both molecules proved to be equally significant inhibitors of isolated EGF-R tyrosine kinases, nevertheless their in vitro antiproliferative activity was variable in cellular assays. Their different inhibitory efficacies could be interpreted on the basis of conformational analysis and lipophilicity evaluation.

Original languageHungarian
Pages (from-to)232-239
Number of pages8
JournalActa Pharmaceutica Hungarica
Volume69
Issue number5
Publication statusPublished - Nov 1999

Fingerprint

Plantago
Protein-Tyrosine Kinases
Epidermal Growth Factor
Growth
Neoplasms
acteoside
6-methoxy-4',5-dihydroxyflavone-7-O-glucoside
In Vitro Techniques

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Kunvári, M., Páska, C., László, M., Őrfi, L., Kövesdi, I., Eros, D., ... Gyurján, I. (1999). Plantago media L antitumor hatoanyagainak szerkezete es biologiai aktivitasa. Acta Pharmaceutica Hungarica, 69(5), 232-239.

Plantago media L antitumor hatoanyagainak szerkezete es biologiai aktivitasa. / Kunvári, Mónika; Páska, Csilla; László, Miklós; Őrfi, L.; Kövesdi, István; Eros, Dániel; Bökönyi, Gyöngyi; Kéri, G.; Gyurján, István.

In: Acta Pharmaceutica Hungarica, Vol. 69, No. 5, 11.1999, p. 232-239.

Research output: Contribution to journalArticle

Kunvári, M, Páska, C, László, M, Őrfi, L, Kövesdi, I, Eros, D, Bökönyi, G, Kéri, G & Gyurján, I 1999, 'Plantago media L antitumor hatoanyagainak szerkezete es biologiai aktivitasa', Acta Pharmaceutica Hungarica, vol. 69, no. 5, pp. 232-239.
Kunvári M, Páska C, László M, Őrfi L, Kövesdi I, Eros D et al. Plantago media L antitumor hatoanyagainak szerkezete es biologiai aktivitasa. Acta Pharmaceutica Hungarica. 1999 Nov;69(5):232-239.
Kunvári, Mónika ; Páska, Csilla ; László, Miklós ; Őrfi, L. ; Kövesdi, István ; Eros, Dániel ; Bökönyi, Gyöngyi ; Kéri, G. ; Gyurján, István. / Plantago media L antitumor hatoanyagainak szerkezete es biologiai aktivitasa. In: Acta Pharmaceutica Hungarica. 1999 ; Vol. 69, No. 5. pp. 232-239.
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