Biochemical and physiological effects of long-term sublethal T-2 toxin feeding in rabbits.

M. Szilágyi, S. Fekete, G. Huszenicza, M. Albert

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Effects of 4-7-week feeding of naturally contaminated wheat grains containing 0.284 mg T-2 toxin/kg were investigated on the health, certain serum biochemical parameters and reproductive status of sexually mature, virgin female rabbits. Three of the ten contaminated animals died before the end of the experiment (acute, fibrinous-purulent peritonitis and pneumonia). Hepatic damages are suggested by significant serum alanine aminotransferase and slight aspartate aminotransferase, gamma-glutamyl transferase, malate dehydrogenase activity increases, as well as by cholinesterase activity decrease as compared to control animals. The damage of kidney function is indicated by significantly higher creatinine level, as compared to the control. The T-2 toxin feeding also impaired ovarian functions, reflecting by unaltered progesteron concentration, macro- and microscopical pictures after GnRH-stimulation.

Original languageEnglish
Pages (from-to)69-76
Number of pages8
JournalActa Biologica Hungarica
Volume45
Issue number1
Publication statusPublished - 1994

Fingerprint

T-2 Toxin
T-2 toxin
toxin
long term effects
serum
Animals
rabbits
Rabbits
reproductive status
Malate Dehydrogenase
damage
blood chemistry
pneumonia
gamma-glutamyltransferase
peritonitis
animal
cholinesterase
malate dehydrogenase
virgin females
Cholinesterases

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

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Biochemical and physiological effects of long-term sublethal T-2 toxin feeding in rabbits. / Szilágyi, M.; Fekete, S.; Huszenicza, G.; Albert, M.

In: Acta Biologica Hungarica, Vol. 45, No. 1, 1994, p. 69-76.

Research output: Contribution to journalArticle

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