Binding of low molecular mass compounds to proteins studied by liquid chromatographic techniques

Tibor Cserháti, Esther Forgács, Zdenek Deyl, Iran Miksik, Adam Echardt

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The newest achievements in the application of miscellaneous liquid chromatographic techniques such as size-exclusion, ion-exchange and reversed-phase high-performance liquid chromatography, and thin-layer chromatography for the elucidation of the various aspects of the binding of ligands to proteins are compiled and briefly discussed. Examples of employment in pharmaceutical and clinical chemistry, drug design, enzyme kinetic studies and environmental protection are presented.

Original languageEnglish
Pages (from-to)353-360
Number of pages8
JournalBiomedical Chromatography
Volume17
Issue number6
DOIs
Publication statusPublished - Sep 1 2003

Keywords

  • Ion-exchange chromatography
  • Reversed-phase high-performance liquid chromatography
  • Size-exclusion chromatography
  • Thin-layer chromatography

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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