Binding of lectins (Con-A, lens, helix, PHA) to binding sites induced in Tetrahymena by insulin and lectins.

G. Csaba, P. Kovács

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Abstract

Concanavalin-A (Con-A) gave rise to a moderate aggregation in untreated (control) Tetrahymena pyriformis GL populations. The cells pretreated (imprinted) with insulin or lectins underwent aggregation earlier and to a greater degree than the untreated control cells. Lens lectin, although of the same sugar specificity as Con-A, was considerably less active than the latter. Helix lectin and phytohaemagglutinin (PHA), although of similar sugar specificity, accounted for a dissimilar extent of cell aggregation, in that Helix lectin was comparable in activity to Con-A. Pretreatment (imprinting) with insulin enhanced the aggregation inducing effect of those lectins which were capable of overlapping on the insulin receptor owing to similar specificity.

Original languageEnglish
Pages (from-to)29-32
Number of pages4
JournalActa microbiologica Hungarica
Volume38
Issue number1
Publication statusPublished - 1991

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ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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