Behavioural impairment induced by calcitonin gene-related peptide (CGRP) antiserum in passive avoidance reflex in rats

A. Kovács, G. Telegdy

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The effects of CGRP antiserum on passive avoidance behaviour were tested in rats. Intracerebroventricular (i.c.v.) administration of CGRP antiserum immediately after a single learning trial attenuated the passive avoidance responses when the animals were tested for 24 h retention. Significant decreases in avoidance latency were found at CGRP antiserum dilutions of 1:20 and 1:40. The data supported the assumption that endogenous brain CGRP may be a modulator in learning-associated memory processes.

Original languageEnglish
Pages (from-to)233-236
Number of pages4
JournalNeuropeptides
Volume26
Issue number4
DOIs
Publication statusPublished - 1994

Fingerprint

Calcitonin Gene-Related Peptide
Reflex
Rats
Immune Sera
Learning
Avoidance Learning
Modulators
Dilution
Brain
Animals
Data storage equipment

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Clinical Neurology
  • Neuroscience(all)
  • Cellular and Molecular Neuroscience

Cite this

Behavioural impairment induced by calcitonin gene-related peptide (CGRP) antiserum in passive avoidance reflex in rats. / Kovács, A.; Telegdy, G.

In: Neuropeptides, Vol. 26, No. 4, 1994, p. 233-236.

Research output: Contribution to journalArticle

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