Behavioural changes in mothers and maternally sensitised female mice

Éva R. Szabó, Melinda Cservenák, Thomas A. Lutz, Lorinc Gévai, Miklós Endrényi, László Simon, A. Dobolyi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The maternal motivation and depression-like behaviour of primiparous mother and maternally sensitised virgin female mice were investigated. During a 1-h test period, dams and sensitised female mice spent significantly more time in pup-associated than in control cages when they could freely choose between them, while virgin control and ovariectomised females had no such preference. In the forced swim test, the time spent in active (swimming and struggling) and passive (floating) behaviours was measured for 6 min. Mother mice spent more time engaged in active behaviours than virgin and sensitised female mice, while the latter two groups did not differ from each other in the forced swim test. The results suggest that maternal motivation is increased in postpartum mothers and maternally sensitised female mice. We also provide the first demonstration that postpartum mother mice display anti-depression-like behaviours in the forced swim test, while maternally sensitised females do not show such emotional changes.

Original languageEnglish
Pages (from-to)1801-1819
Number of pages19
JournalBehaviour
Volume152
Issue number12-13
DOIs
Publication statusPublished - 2015

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mice
Postpartum Period
Motivation
testing
Mothers
Depression
virgin females
pups
cages

Keywords

  • Evaluation of laboratory animal tracking
  • Forced swim test
  • Maternal motivation
  • Mouse dams
  • Postpartum depression
  • Pup-induced conditioned place preference
  • Sensitised behaviour

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Behavioral Neuroscience

Cite this

Szabó, É. R., Cservenák, M., Lutz, T. A., Gévai, L., Endrényi, M., Simon, L., & Dobolyi, A. (2015). Behavioural changes in mothers and maternally sensitised female mice. Behaviour, 152(12-13), 1801-1819. https://doi.org/10.1163/1568539X-00003305

Behavioural changes in mothers and maternally sensitised female mice. / Szabó, Éva R.; Cservenák, Melinda; Lutz, Thomas A.; Gévai, Lorinc; Endrényi, Miklós; Simon, László; Dobolyi, A.

In: Behaviour, Vol. 152, No. 12-13, 2015, p. 1801-1819.

Research output: Contribution to journalArticle

Szabó, ÉR, Cservenák, M, Lutz, TA, Gévai, L, Endrényi, M, Simon, L & Dobolyi, A 2015, 'Behavioural changes in mothers and maternally sensitised female mice', Behaviour, vol. 152, no. 12-13, pp. 1801-1819. https://doi.org/10.1163/1568539X-00003305
Szabó ÉR, Cservenák M, Lutz TA, Gévai L, Endrényi M, Simon L et al. Behavioural changes in mothers and maternally sensitised female mice. Behaviour. 2015;152(12-13):1801-1819. https://doi.org/10.1163/1568539X-00003305
Szabó, Éva R. ; Cservenák, Melinda ; Lutz, Thomas A. ; Gévai, Lorinc ; Endrényi, Miklós ; Simon, László ; Dobolyi, A. / Behavioural changes in mothers and maternally sensitised female mice. In: Behaviour. 2015 ; Vol. 152, No. 12-13. pp. 1801-1819.
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