Natural killer cell (NK) activity of peripheral blood lymphocytes against K-562 cells was investigated in lichen planus (LP). 38 LP patients with cutaneous or oral mucosal involvement and 20 healthy controls participated in the study. A statistically significant decrease in the NK response in LP patients with extensive erosive oral mucosal involvement (p < 0.02) and in generalized acute eruptive LP (p < 0.01) was noted compared to those with nonerosive LP of the oral mucosa or healthy controls. Interleukin 2 failed to restore completely the reduced NK activities in our patients with LP.
|Number of pages||4|
|Publication status||Published - Jan 1 1989|
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