Basic and interleukin-2-augmented natural killer cell activity in lichen planus

M. Simon, J. Hunyadi, H. Fickentscher, O. P. Hornstein

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6 Citations (Scopus)

Abstract

Natural killer cell (NK) activity of peripheral blood lymphocytes against K-562 cells was investigated in lichen planus (LP). 38 LP patients with cutaneous or oral mucosal involvement and 20 healthy controls participated in the study. A statistically significant decrease in the NK response in LP patients with extensive erosive oral mucosal involvement (p < 0.02) and in generalized acute eruptive LP (p < 0.01) was noted compared to those with nonerosive LP of the oral mucosa or healthy controls. Interleukin 2 failed to restore completely the reduced NK activities in our patients with LP.

Original languageEnglish
Pages (from-to)141-144
Number of pages4
JournalDermatologica
Volume178
Issue number3
Publication statusPublished - Jan 1 1989

ASJC Scopus subject areas

  • Dermatology

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    Simon, M., Hunyadi, J., Fickentscher, H., & Hornstein, O. P. (1989). Basic and interleukin-2-augmented natural killer cell activity in lichen planus. Dermatologica, 178(3), 141-144.