Autonomic cold- and heat-defence of rats during a febrile rise in core temperature induced by intracerebroventricular infusion of prostaglandin E1

Z. Szelényi, M. Székely, Lilla Czippán

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Body core temperature of rats is elevated during intracerebroventricular infusions of prostaglandin E1. In the course of concurrent acute cold- or warm-exposure this new elevated temperature is defended to the same extent as is normal temperature in control animals. Skin vasomotor changes - reflected by oscillations of tail-skin temperature - suggest, however, a decreased regulatory accuracy (or sensitivity) during PGE1 infusion, at least when measured at thermoneutral ambient temperature.

Original languageEnglish
Pages (from-to)219-226
Number of pages8
JournalPathophysiology
Volume3
Issue number4
DOIs
Publication statusPublished - Dec 1996

Fingerprint

Intraventricular Infusions
Alprostadil
Fever
Hot Temperature
Temperature
Skin Temperature
Body Temperature
Tail
Skin

Keywords

  • Cold-defence
  • Fever
  • Heat-defence
  • Hyperthermia
  • Intracerebroventricular infusion
  • Prostaglandin E
  • Sensitivity of regulation
  • Thermoregulation
  • Thermoregulatory set-point

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

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title = "Autonomic cold- and heat-defence of rats during a febrile rise in core temperature induced by intracerebroventricular infusion of prostaglandin E1",
abstract = "Body core temperature of rats is elevated during intracerebroventricular infusions of prostaglandin E1. In the course of concurrent acute cold- or warm-exposure this new elevated temperature is defended to the same extent as is normal temperature in control animals. Skin vasomotor changes - reflected by oscillations of tail-skin temperature - suggest, however, a decreased regulatory accuracy (or sensitivity) during PGE1 infusion, at least when measured at thermoneutral ambient temperature.",
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T1 - Autonomic cold- and heat-defence of rats during a febrile rise in core temperature induced by intracerebroventricular infusion of prostaglandin E1

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AU - Székely, M.

AU - Czippán, Lilla

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