Automatic dendrite spines detection from x-ray tomography volumes

Xavier Descombes, Gregoire Malandain, Caroline Fonta, Lazlo Negyessy, Rajmund Mosko

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We consider the problem of dendritic spine detection from X-ray micro-tomographic volumes that allow huge volume of tissue visualization. To compensate for the noise in data that induces false positives in the spine detection process, we first segment the dendrites. This segmentation is obtained by computing the medial axis and approximating the results by segments obtained with a 3D Hough transform. Dendrites are then reconstructed and a spine mask is obtained using the typical diameter of dendrites and distance between spine and dendrites. A point process is then optimized on this mask, thus providing the spine detection.

Original languageEnglish
Title of host publicationISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro
Pages436-439
Number of pages4
DOIs
Publication statusPublished - Aug 22 2013
Event2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States
Duration: Apr 7 2013Apr 11 2013

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
CountryUnited States
CitySan Francisco, CA
Period4/7/134/11/13

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Keywords

  • 3D Hough transform
  • Dendritic spine
  • Point Process
  • X-Ray micro-tomography

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Descombes, X., Malandain, G., Fonta, C., Negyessy, L., & Mosko, R. (2013). Automatic dendrite spines detection from x-ray tomography volumes. In ISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro (pp. 436-439). [6556505] (Proceedings - International Symposium on Biomedical Imaging). https://doi.org/10.1109/ISBI.2013.6556505