A CANTAB alkalmazása depresszióban - elo{double acute}zetes adatok

Translated title of the contribution: Automated neuropsychological test battery in depression - preliminary data

Aniko Egerhazi, Petra Balla, Andrea Ritzl, Zsofia Varga, Ede Frecska, R. Berecz

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Aims: Studies have demonstrated neuropsychological deficits across a variety of cognitive domains in patients with major depressive disorder (MDD) during acute episode. However, limited data are available concerning whether these abnormalities persist in the remission phase. Methods: In the present study CANTAB (Cambridge Automated Neuropsychological Test Battery) was used to evaluate the cognitive impairment associated with depression during acute episode and in remission. 25 patients with MDD during an acute episode and 11 patients also during remission were tested with CANTAB. Results: During the acute episode, Delayed matching to sample, Paired associate learning, Spatial recognition memory, Rapid visual processing and Visuospatial planning were impaired. In remission the improvement of visual learning ability, spatial recognition memory, psychomotor speed, and executive function was observed. Conclusions: The results suggest that MDD is associated with neurocognitive dysfunctions in different domains, the most prominent deficit was found in the Paired associate learning test, which requires both the elaboration of"frontal strategies" and the"mnemonic processes". Cognitive impairment was found to improve partly in remission, suggesting that an individual's current mood interacts with the ability to perform a cognitive task. Besides these state markers, trait deficits are important because cognitive impairments which do not improve in remission might serve as endophenotypes of depression.

Original languageHungarian
Pages (from-to)5-11
Number of pages7
JournalNeuropsychopharmacologia Hungarica
Volume15
Issue number1
Publication statusPublished - 2013

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Neuropsychological Tests
Major Depressive Disorder
Paired-Associate Learning
Aptitude
Depression
Endophenotypes
Executive Function
Learning
Cognitive Dysfunction
Spatial Memory
Recognition (Psychology)

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Neuropsychology and Physiological Psychology
  • Clinical Neurology

Cite this

Egerhazi, A., Balla, P., Ritzl, A., Varga, Z., Frecska, E., & Berecz, R. (2013). A CANTAB alkalmazása depresszióban - elo{double acute}zetes adatok. Neuropsychopharmacologia Hungarica, 15(1), 5-11.

A CANTAB alkalmazása depresszióban - elo{double acute}zetes adatok. / Egerhazi, Aniko; Balla, Petra; Ritzl, Andrea; Varga, Zsofia; Frecska, Ede; Berecz, R.

In: Neuropsychopharmacologia Hungarica, Vol. 15, No. 1, 2013, p. 5-11.

Research output: Contribution to journalArticle

Egerhazi, A, Balla, P, Ritzl, A, Varga, Z, Frecska, E & Berecz, R 2013, 'A CANTAB alkalmazása depresszióban - elo{double acute}zetes adatok', Neuropsychopharmacologia Hungarica, vol. 15, no. 1, pp. 5-11.
Egerhazi, Aniko ; Balla, Petra ; Ritzl, Andrea ; Varga, Zsofia ; Frecska, Ede ; Berecz, R. / A CANTAB alkalmazása depresszióban - elo{double acute}zetes adatok. In: Neuropsychopharmacologia Hungarica. 2013 ; Vol. 15, No. 1. pp. 5-11.
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