Automated Neuropsychological Test Battery (CANTAB) in mild cognitive impairment and in Alzheimer's disease

Anikó Égerházi, Roland Berecz, Eniko Bartók, István Degrell

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

Neuropsychological deficits, such as poor episodic memory, are consistent features of mild cognitive impairment and also that of early stage of dementia. The aim of the present study was to detect cognitive dysfunction among patients with Alzheimer's disease or with mild cognitive impairment (MCI), which refers to a transitional state between the cognition of normal aeging and mild dementia regarded as a high-risk condition for the development of clinically probable Alzheimer's disease (AD). Computerized tests of memory, attention and executive functions were studied in groups of AD subjects (n = 15) and MCI subjects (n = 25). On all measures, the performance of the AD group was significantly weaker compared to healthy individuals or to the MCI group. The performance of both the AD and MCI patients in the Paired Associate Learning test was significantly impaired, which may suggest that MCI patients are already in the early stages of the disease.

Original languageEnglish
Pages (from-to)746-751
Number of pages6
JournalProgress in Neuro-Psychopharmacology and Biological Psychiatry
Volume31
Issue number3
DOIs
Publication statusPublished - Apr 30 2007

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Keywords

  • Alzheimer's disease
  • Cognitive dysfunctions
  • Computerized neuropsychological test battery
  • Early diagnosis
  • Mild cognitive impairment
  • Paired associate learning task

ASJC Scopus subject areas

  • Pharmacology
  • Biological Psychiatry

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