Autoimmun pancreatitis - Aluldiagnosztizált kórkép?

Translated title of the contribution: Autoimmune pancreatitis - An underdiagnosed disease?

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Autoimmune pancreatitis is a recently recognized type of chronic pancreatitis that is clearly distinct from alcoholic chronic pancreatitis. Its clinical symptoms include jaundice, abdominal pain, weight loss and diabetes mellitus. It may be associated with other autoimmune diseases. IgG levels are elevated and autoantibodies can be detected. Pancreatic imaging reveals a diffuse enlargement of the pancreas and irregular narrowing of the main pancreatic duct. The characteristic histological features are lymphoplasmacytic infiltration and fibrosis. Autoimmune pancreatitis responds dramatically to steroid therapy, in contrast to other types of chronic pancreatitis, which hardly respond to any of the various therapies. It is important to be aware of this disease because it may be mistaken for other forms of chronic pancreatitis or pancreatic cancer, which leads to pancreatic resection when steroid treatment would be sufficient. This review discusses the clinical, laboratory, histological and imaging findings that are seen in autoimmune pancreatitis with particular focus on diagnosis. With the improvement of the diagnostic work-up less unnecessary pancreatic resections are expected to happen in patients with autoimmune pancreatitis.

Original languageHungarian
Pages (from-to)505-510
Number of pages6
JournalLege Artis Medicinae
Volume16
Issue number6
Publication statusPublished - Jun 2006

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Chronic Pancreatitis
Pancreatitis
Steroids
Alcoholic Pancreatitis
Pancreatic Ducts
Jaundice
Pancreatic Neoplasms
Autoantibodies
Abdominal Pain
Autoimmune Diseases
Weight Loss
Pancreas
Diabetes Mellitus
Fibrosis
Therapeutics
Immunoglobulin G

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Autoimmun pancreatitis - Aluldiagnosztizált kórkép? / Czakó, L.

In: Lege Artis Medicinae, Vol. 16, No. 6, 06.2006, p. 505-510.

Research output: Contribution to journalArticle

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