Az autoimmun haemolyticus anaemiáról négy eset kapcsán

Translated title of the contribution: Autoimmune haemolytic anaemia: A review and report of four cases

Renáta Nyilas, Borbála Székely, László Váróczy, Zsófia Simon, Anita Árokszállási, A. Illés, L. Gergely

Research output: Contribution to journalArticle

Abstract

Treatment of autoimmune haemolytic anaemia is still a challenge to clinicians. Even today it may be lethal. Half of the cases are secondary due to an underlying disease, and the others are primary or idiopathic cases. According to the specificity and type of autoantibodies there are warm and cold type forms of autoimmune haemolytic anaemia. The hallmark of the diagnosis is to detect the presence of haemolysis by clinical and laboratory signs and detect the underlying autoantibodies. Treatment of autoimmune haemolytic anaemia is still a challenge to clinicians. We still loose patients due to excessive haemolysis or severe infections caused by immunosuppression. First line treatment is corticosteroids. Other immunosuppressive agents like: cyclophosphamide, azathioprine, cyclosporine or the off label rituximab can be used in case of corticosteroid refractoriness. Splenectomy is a considerable option in selective cases. The authors discuss treatment options and highlight difficulties by presenting 4 cases.

Original languageHungarian
Pages (from-to)449-456
Number of pages8
JournalOrvosi Hetilap
Volume156
Issue number11
DOIs
Publication statusPublished - Mar 11 2015

Fingerprint

Autoimmune Hemolytic Anemia
Hemolysis
Autoantibodies
Adrenal Cortex Hormones
Azathioprine
Splenectomy
Therapeutics
Immunosuppressive Agents
Cyclophosphamide
Immunosuppression
Cyclosporine
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nyilas, R., Székely, B., Váróczy, L., Simon, Z., Árokszállási, A., Illés, A., & Gergely, L. (2015). Az autoimmun haemolyticus anaemiáról négy eset kapcsán. Orvosi Hetilap, 156(11), 449-456. https://doi.org/10.1556/OH.2015.30105

Az autoimmun haemolyticus anaemiáról négy eset kapcsán. / Nyilas, Renáta; Székely, Borbála; Váróczy, László; Simon, Zsófia; Árokszállási, Anita; Illés, A.; Gergely, L.

In: Orvosi Hetilap, Vol. 156, No. 11, 11.03.2015, p. 449-456.

Research output: Contribution to journalArticle

Nyilas, R, Székely, B, Váróczy, L, Simon, Z, Árokszállási, A, Illés, A & Gergely, L 2015, 'Az autoimmun haemolyticus anaemiáról négy eset kapcsán', Orvosi Hetilap, vol. 156, no. 11, pp. 449-456. https://doi.org/10.1556/OH.2015.30105
Nyilas R, Székely B, Váróczy L, Simon Z, Árokszállási A, Illés A et al. Az autoimmun haemolyticus anaemiáról négy eset kapcsán. Orvosi Hetilap. 2015 Mar 11;156(11):449-456. https://doi.org/10.1556/OH.2015.30105
Nyilas, Renáta ; Székely, Borbála ; Váróczy, László ; Simon, Zsófia ; Árokszállási, Anita ; Illés, A. ; Gergely, L. / Az autoimmun haemolyticus anaemiáról négy eset kapcsán. In: Orvosi Hetilap. 2015 ; Vol. 156, No. 11. pp. 449-456.
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