The aim of our present study was to examine the ADCC reaction against liver cell in various chronic liver diseases on the basis of indirect evidence. Forty-nine liver patients and one hundred and twenty-three healthy controls were examined. Anti-LSP autoantibody was determined on rat liver membrane by using the indirect immunofluorescent method. On the other hand, Killer-cell activity against human erythrocyte target cells was established in the lymphocytes of peripheral blood. Anti-LSP autoantibodies were demonstrated in seven patients and were associated with the high Killer-cell activity in six cases. Specific ADCC reaction to liver cell membrane can be assumed if anti-LSP autoantibody presence is topped with increased Killer-cell activity.
|Number of pages||9|
|Journal||Acta medica Hungarica|
|Publication status||Published - 1991|
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