Autoantibody against liver cell membrane and killer cell activity in chronic liver diseases.

R. Schnabel, L. Dalmi, S. Sipka, M. Bokor, G. Malatinszky, T. Garam

Research output: Contribution to journalArticle

Abstract

The aim of our present study was to examine the ADCC reaction against liver cell in various chronic liver diseases on the basis of indirect evidence. Forty-nine liver patients and one hundred and twenty-three healthy controls were examined. Anti-LSP autoantibody was determined on rat liver membrane by using the indirect immunofluorescent method. On the other hand, Killer-cell activity against human erythrocyte target cells was established in the lymphocytes of peripheral blood. Anti-LSP autoantibodies were demonstrated in seven patients and were associated with the high Killer-cell activity in six cases. Specific ADCC reaction to liver cell membrane can be assumed if anti-LSP autoantibody presence is topped with increased Killer-cell activity.

Original languageEnglish
Pages (from-to)23-31
Number of pages9
JournalActa Medica Hungarica
Volume48
Issue number1-2
Publication statusPublished - 1991

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Autoantibodies
Liver Diseases
Chronic Disease
Cell Membrane
Liver
Antibody-Dependent Cell Cytotoxicity
Human Activities
Erythrocytes
Lymphocytes
Membranes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Schnabel, R., Dalmi, L., Sipka, S., Bokor, M., Malatinszky, G., & Garam, T. (1991). Autoantibody against liver cell membrane and killer cell activity in chronic liver diseases. Acta Medica Hungarica, 48(1-2), 23-31.

Autoantibody against liver cell membrane and killer cell activity in chronic liver diseases. / Schnabel, R.; Dalmi, L.; Sipka, S.; Bokor, M.; Malatinszky, G.; Garam, T.

In: Acta Medica Hungarica, Vol. 48, No. 1-2, 1991, p. 23-31.

Research output: Contribution to journalArticle

Schnabel, R, Dalmi, L, Sipka, S, Bokor, M, Malatinszky, G & Garam, T 1991, 'Autoantibody against liver cell membrane and killer cell activity in chronic liver diseases.', Acta Medica Hungarica, vol. 48, no. 1-2, pp. 23-31.
Schnabel, R. ; Dalmi, L. ; Sipka, S. ; Bokor, M. ; Malatinszky, G. ; Garam, T. / Autoantibody against liver cell membrane and killer cell activity in chronic liver diseases. In: Acta Medica Hungarica. 1991 ; Vol. 48, No. 1-2. pp. 23-31.
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