Autoantibodies specific to β2-microglobulin inhibit the Fc receptor-dependent phagocytosis of human monocytes

A. Falus, Mária Kávai, Katalin Merétey, S. Bozsóky

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Effect of anti-β2-microglobulin (β2m) antibodies was investigated on the in vitro Fc and C3 receptor-dependent phagocytic capacity of human peripheral monocytes. Both rabbit and human anti-β2m antibodies inhibit the Fc receptor-mediated phagocytosis. Anti-β2m antibodies do not influence the spontaneous or C3b receptor-mediated ingestion. The inhibitory activity by human autoantibodies but not by rabbit anti-human β2m antibodies was diminished when incubation was performed at 37°C instead of 20°C.

Original languageEnglish
Pages (from-to)45-49
Number of pages5
JournalImmunology Letters
Volume3
Issue number1
DOIs
Publication statusPublished - 1981

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Fc Receptors
Phagocytosis
Autoantibodies
Monocytes
Antibodies
Complement 3b Receptors
Rabbits
Human Activities
Eating

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Autoantibodies specific to β2-microglobulin inhibit the Fc receptor-dependent phagocytosis of human monocytes. / Falus, A.; Kávai, Mária; Merétey, Katalin; Bozsóky, S.

In: Immunology Letters, Vol. 3, No. 1, 1981, p. 45-49.

Research output: Contribution to journalArticle

Falus, A. ; Kávai, Mária ; Merétey, Katalin ; Bozsóky, S. / Autoantibodies specific to β2-microglobulin inhibit the Fc receptor-dependent phagocytosis of human monocytes. In: Immunology Letters. 1981 ; Vol. 3, No. 1. pp. 45-49.
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