In the United States, the updated classification of The Bethesda System (TBS 2001) combined the various categories of cervical cytology. TBS (2001) introduced two important subgroups of ASC (atypical squamous cells) diagnostic category - ASC-US (atypical squamous cells of undetermined significance) and ASC-H (atypical squamous cells, that cannot exclude high grade squamous intraepithelial lesion (H-SIL)). The authors' aim was to classify the ASC cytological diagnoses according to TBS (2001), carry out a follow up and a retrospective cyto-histological comparison. ASC diagnosis was made in 347 cases (2.8%) of the 12378 cervical smears. ASC-US was found in 321 patients (2.6%), while ASC-H in 26 cases respectively (0.2%). Histological data were available in 54 of the ASC-US (P3) cases, and proved negative in 57%, in SIL (CIN I, II, III, carcinoma in situ) - in 41%, in L-SIL (CIN I) - in 11%, in H-SIL (CIN II, III, carcinoma in situ) - in 30%, and in early invasive carcinomas - in 2%. Histology of ASC-H (P4) lesions was benign in 19%, in H-SIL- in 75%, and in early invasive carcinomas -in 6%. Both the ASC cervical cytological categories are very important from diagnostic point of view and the patients must always be informed regarding these findings.
|Translated title of the contribution||Atypical squamous cells (ASC) (TBS-2001) (cervical-histological study)|
|Number of pages||4|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Dec 1 2004|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology