Atypischer verlauf einer akuten leberfunktionsstorung mit schwerer thrombozytopenie im dritten trimester

Translated title of the contribution: Atypical process of acute disturbance of liver-function associated with severe thrombocytopenia in the third trimester

Jr Rigo J., J. Tanyi, I. Varga, E. Gorbe

Research output: Contribution to journalArticle

Abstract

The authors diagnosed disturbance of liver-function associated with severe thrombopenia in a pregnant woman in the third trimester. Principally, acute fatty liver of pregnancy can be characterized by existing symptoms, e.g. nausea, vomiting, epigastric pain, jaundice, hyperbilirubinemia, moderately elevated SGOT and SGPT levels, thrombopenia, leukocytosis, low fibrinogen level and disseminated intravascular coagulopathy, but hepatomegaly, purpura and petechia on lower and upper extremities, and high ALP and GGT levels during postpartum period do not confirm suspicion of this diagnosis. The present report draws attention to the difficulties of differential diagnosis of pregnancy-induced elevated liver enzymes diseases associated with low platelets, as there are several identical pathophysiological processes. Although causes and exact pathophysiology of disorders are unknown, similar symptoms during the process of diseases leave the question open whether they are different diseases or whether they are different manifestations of the same disease, and what kind of relationship exists between these diseases and preeclampsia. This case suggests careful evaluation of the whole clinical picture, moreover it is emphasized that prompt, aggressive treatment of hemostatic disturbance and the expeditious delivery can save maternal life.

Translated title of the contributionAtypical process of acute disturbance of liver-function associated with severe thrombocytopenia in the third trimester
Original languageGerman
Pages (from-to)436-438
Number of pages3
JournalZentralblatt fur Gynakologie
Volume122
Issue number8
DOIs
Publication statusPublished - Jan 1 2000

Keywords

  • Liver disease
  • Pregnancy
  • Thrombocytopenia

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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