Asymmetric synthesis of cis 3-phthalimido-4-styryl-2-azetidinones. Application of a new chiral N-protecting group in monobactam chemistry

Tamas E. Gunda, F. Sztaricskai

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

1-N-(1′-p-Nitrophenyl-1′,3′-dihydroxy-2-propyl)-3-phth alimido-4-styrylazetidin-2-ones (6a-d), obtained in optically pure form via chiral Staudinger reactions, were transformed to the N-deprotected derivatives (8a,b) by means of a two-step oxidative procedure.

Original languageEnglish
Pages (from-to)2379-2392
Number of pages14
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number11
DOIs
Publication statusPublished - Nov 1993

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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