Asymmetric hydroformylation with Pt-phosphine-SnCl2 and Pt-bisphosphine-CuCl2 (or CuCl) catalytic systems

László Kollár, József Bakos, Imre Tóth, Bálint Heil

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

A study has been made of asymmetric hydroformylation of styrene with PtCl2(PPh3)2 + bisphosphine + SnCl2 (bisphosphine: BDPP = (-)-(2S,4S)-2,4-bis(diphenylphosphino)pentane or DIOP = (-)-(4R,5R)-2,2-dimethyl-4,5-bis(diphenylphosphinomethyl)-1,3-dioxolane) and PtCl2(bisphosphine) + PPh3 + SnCl2 catalysts prepared "in situ". The presence of an excess of the phosphine ligand slightly lowered the reaction rate, but the enantioselectivity of these systems is significantly higher than those involving PtCl(SnCl3)(bisphosphine) catalysts. Under mild reaction conditions 88.8% enantiomeric excess was achieved. Replacing SnCl2 in these catalysts by CuCl2 or CuCl gave a new homogeneous catalytic system which is active at higher reaction temperature (> 100°C), but has a rather moderate enantioselectivity.

Original languageEnglish
Pages (from-to)257-261
Number of pages5
JournalJournal of Organometallic Chemistry
Volume370
Issue number1-3
DOIs
Publication statusPublished - Jul 11 1989

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

Cite this