Asymmetric biotransformations in continuous flow reactors

Zoltán Boros, Mariann Szigeti, Anna Tomin, Péter Kovács, László Ürge, Ferenc Darvas, László Poppe

Research output: Contribution to journalArticle

2 Citations (Scopus)


Asymmetric acetylations of prochiral diols 3a-d with isopropenyl acetate were investigated with different commercial and self prepared lipases. Continuous flow mode reactions were performed in small stainless steel packed-bed reactors which can precisely control temperature (-10-200 °C), pressure (0-150 bar) and flow rate (0.1-3.0 mL/min). The effect of the temperature and flow-rate on the conversion and enantiomer excess of the chiral monoesters was investigated.

Original languageEnglish
Pages (from-to)69-75
Number of pages7
JournalStudia Universitatis Babes-Bolyai Chemia
Issue numberSPEC.ISSUE 2
Publication statusPublished - Dec 1 2009



  • Asymmetric biotransformation
  • Continuous flow reactor
  • Lipase

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Boros, Z., Szigeti, M., Tomin, A., Kovács, P., Ürge, L., Darvas, F., & Poppe, L. (2009). Asymmetric biotransformations in continuous flow reactors. Studia Universitatis Babes-Bolyai Chemia, (SPEC.ISSUE 2), 69-75.