Astroviruses in rabbits

Vito Martella, Paschalina Moschidou, Pierfrancesco Pinto, Cristiana Catella, Constantina Desario, Vittorio Larocca, Elena Circella, K. Bányai, Antonio Lavazza, Chiara Magistrali, Nicola Decaro, Canio Buonavoglia

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

By screening rabbits with enterocolitis or enteritis complex and asymptomatic rabbits, we identified a novel astrovirus. The virus was distantly related (19.3%-23.7% aa identity) in the capsid precursor to other mammalian astroviruses within the Mamastrovirus genus. By using realtime reverse transcription PCR, with specific primers and probes and targeting a conserved stretch in open reading frame 1b, we found rabbit astrovirus in 10 (43%) of 23 samples from animals with enteric disease and in 25 (18%) of 139 samples from asymptomatic animals in Italy during 2005-2008. The mean and median titers in the positive animals were 102× and 103× greater, respectively, in the symptomatic animals than in the asymptomatic animals. These findings support the idea that rabbit astroviruses should be included in the diagnostic algorithm of rabbit enteric disease and animal experiments to increase information obtained about their epidemiology and potential pathogenic role.

Original languageEnglish
Pages (from-to)2287-2293
Number of pages7
JournalEmerging Infectious Diseases
Volume17
Issue number12
DOIs
Publication statusPublished - 2011

Fingerprint

Rabbits
Mamastrovirus
Enterocolitis
Enteritis
Capsid
Italy
Open Reading Frames
Reverse Transcription
Epidemiology
Viruses
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

Cite this

Martella, V., Moschidou, P., Pinto, P., Catella, C., Desario, C., Larocca, V., ... Buonavoglia, C. (2011). Astroviruses in rabbits. Emerging Infectious Diseases, 17(12), 2287-2293. https://doi.org/10.3201/eid1712.110967

Astroviruses in rabbits. / Martella, Vito; Moschidou, Paschalina; Pinto, Pierfrancesco; Catella, Cristiana; Desario, Constantina; Larocca, Vittorio; Circella, Elena; Bányai, K.; Lavazza, Antonio; Magistrali, Chiara; Decaro, Nicola; Buonavoglia, Canio.

In: Emerging Infectious Diseases, Vol. 17, No. 12, 2011, p. 2287-2293.

Research output: Contribution to journalArticle

Martella, V, Moschidou, P, Pinto, P, Catella, C, Desario, C, Larocca, V, Circella, E, Bányai, K, Lavazza, A, Magistrali, C, Decaro, N & Buonavoglia, C 2011, 'Astroviruses in rabbits', Emerging Infectious Diseases, vol. 17, no. 12, pp. 2287-2293. https://doi.org/10.3201/eid1712.110967
Martella V, Moschidou P, Pinto P, Catella C, Desario C, Larocca V et al. Astroviruses in rabbits. Emerging Infectious Diseases. 2011;17(12):2287-2293. https://doi.org/10.3201/eid1712.110967
Martella, Vito ; Moschidou, Paschalina ; Pinto, Pierfrancesco ; Catella, Cristiana ; Desario, Constantina ; Larocca, Vittorio ; Circella, Elena ; Bányai, K. ; Lavazza, Antonio ; Magistrali, Chiara ; Decaro, Nicola ; Buonavoglia, Canio. / Astroviruses in rabbits. In: Emerging Infectious Diseases. 2011 ; Vol. 17, No. 12. pp. 2287-2293.
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