Association study of the ABCA7 rs3752246 polymorphism in Alzheimer's disease

Ágnes Fehér, A. Juhász, Magdolna Pákáski, Zoltán Janka, János Kálmán

Research output: Contribution to journalLetter


The ATP-binding cassette, sub-family A, member 7 (ABCA7) gene has been identified as a strong genetic risk locus for Alzheimer's disease (AD). Our case-control study (416 AD patients and 302 controls) provides further data on the rs3752246 polymorphism in AD in the Hungarian population that has not been investigated so far regarding the ABCA7 gene variants. A modest, marginally significant association of the G allele containing genotypes with AD was observed (p = 0.054). In line with the previous results in other populations, the G allele carriers had an increased risk for developing AD considering C/C genotype as reference category.

Original languageEnglish
Pages (from-to)376-377
Number of pages2
JournalPsychiatry research
Publication statusPublished - Sep 2019


  • ABCA7
  • APOE
  • Alzheimer's disease
  • Association study
  • rs3752246

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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