Szisztémás lupus erythematosus és Sjögren- szindróma társult eseteinek elemzése

Translated title of the contribution: Association of systemic lupus erythematosus and Sjögren's syndrome

Antónia Szántó, E. Kiss, Attila Sas, G. Szegedi, M. Zeher

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Introduction: Systemic lupus erythematosus and Sjögren's syndrome are polysystemic autoimmune diseases which can be associated to each other. Objective: To investigate if there are any distinct clinical, laboratory or serological features due to the association of the two diseases that can influence the follow up of the patients. Patients and methods: The authors proved the association of these two autoimmun diseases in 56 patients, and these patients' clinical, laboratory and immunoserological alterations. 50 patients with Sjögren's syndrome and 50 patients with systemic lupus erythematosus were used as control groups. Results: Compared with Sjögren's syndrome alone, in the cases of the association of the diseases, rheumatoid factor was present less frequently, Ro/SS-A, La/SS-B and DNA antibodies were present more frequently, such as antiphospholipid autoantibodies and antiphospholipid syndrome. Anaemia, leukopenia and lymphopenia were detected more often and the patients were younger than in Sjögren's syndrome. Also, affection of the lung, kidney, skin, central nervous system and serous membranes are more common. The group with systemic lupus erythematosus differs in being older, having thyroiditis, Ro/SS-A, La/SS-B and DNA more frequently. Conclusion: Definitive clinical, laboratory and serological features make the difference between the association of the two diseases and the diseases observed alone.

Original languageHungarian
Pages (from-to)2533-2538
Number of pages6
JournalOrvosi Hetilap
Volume146
Issue number50
Publication statusPublished - 2005

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Systemic Lupus Erythematosus
Serous Membrane
Thyroiditis
Lymphopenia
Antiphospholipid Syndrome
Rheumatoid Factor
DNA
Leukopenia
Autoantibodies
Autoimmune Diseases
Anemia
Central Nervous System
Kidney
Lung
Control Groups
Skin

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Szisztémás lupus erythematosus és Sjögren- szindróma társult eseteinek elemzése. / Szántó, Antónia; Kiss, E.; Sas, Attila; Szegedi, G.; Zeher, M.

In: Orvosi Hetilap, Vol. 146, No. 50, 2005, p. 2533-2538.

Research output: Contribution to journalArticle

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