Association of Pre-Operative Albuminuria with Post-Operative Outcomes after Coronary Artery Bypass Grafting

Lekha K. George, M. Molnár, Jun L. Lu, Kamyar Kalantar-Zadeh, Santhosh K G Koshy, Csaba P. Kovesdy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The effect on post-operative outcomes after coronary artery bypass graft(CABG) surgery is not clear. Among 17,812 patients who underwent CABG during October 1,2006-September 28,2012 in any Department of US Veterans Affairs(VA) hospital, we identified 5,968 with available preoperative urine albumin-creatinine ratio(UACR) measurements. We examined the association of UACR=300 mg/g with 30/90/180/365-day and overall all-cause mortality, and hospitalization length >10 days, and with acute kidney injury(AKI). Mean ± SD baseline age and eGFR were 66 ± 8 years and 77 ± 19 ml/min/1.73 m2, respectively. 788 patients(13.2%) died during a median follow-up of 3.2 years, and 26.8% patients developed AKI(23.1%-Stage 1; 2.9%-Stage 2; 0.8%-Stage 3) within 30 days of CABG. The median lengths of stay were 8 days(IQR: 6-13 days), 10 days(IQR: 7-14 days) and 12 days(IQR: 8-19 days) for groups with UACR <30 mg/g, 30-299 mg/g and ≥300 mg/g, respectively. Higher UACR conferred 72 to 85% higher 90-, 180-, and 365-day mortality compared to UACR

Original languageEnglish
Article number16458
JournalScientific Reports
Volume5
DOIs
Publication statusPublished - Nov 9 2015

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Albuminuria
Coronary Artery Bypass
Albumins
Creatinine
Urine
Transplants
Acute Kidney Injury
Veterans Hospitals
Mortality
Length of Stay
Hospitalization

ASJC Scopus subject areas

  • General

Cite this

Association of Pre-Operative Albuminuria with Post-Operative Outcomes after Coronary Artery Bypass Grafting. / George, Lekha K.; Molnár, M.; Lu, Jun L.; Kalantar-Zadeh, Kamyar; Koshy, Santhosh K G; Kovesdy, Csaba P.

In: Scientific Reports, Vol. 5, 16458, 09.11.2015.

Research output: Contribution to journalArticle

George, Lekha K. ; Molnár, M. ; Lu, Jun L. ; Kalantar-Zadeh, Kamyar ; Koshy, Santhosh K G ; Kovesdy, Csaba P. / Association of Pre-Operative Albuminuria with Post-Operative Outcomes after Coronary Artery Bypass Grafting. In: Scientific Reports. 2015 ; Vol. 5.
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