Association of adherence to therapy and complementary and alternative medicine use with demographic factors and disease phenotype in patients with inflammatory bowel disease

Peter Laszlo Lakatos, Zsofia Czegledi, Gyula David, Zsofia Kispal, Lajos S. Kiss, Karoly Palatka, Tunde Kristof, Ferenc Nagy, Agnes Salamon, Pal Demeter, Pal Miheller, Tamas Szamosi, Janos Banai, Maria Papp, Laszlo Bene, Agota Kovacs, Istvan Racz, Laszlo Lakatos

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Background and aims: Previous studies have suggested an increasing use of complementary and alternative medicine (CAM) in patients with inflammatory bowel disease (IBD). Furthermore, a significant number of IBD patients fail to comply with treatment. The aim of our study was to evaluate the prevalence of non-adherence and the use of CAM in Hungarian patients with IBD. Methods: A total of 655 consecutive IBD patients (CD: 344, age: 38.2 [SD 12.9]. years; UC: 311, age: 44.9 [15.3]. years) were interviewed during the specialist visit by self-administered questionnaire including demographic and disease-related data as well as items analyzing the extent of non-adherence and CAM use. Patients taking more than 80% of each prescribed medication were classified as adherent. Results: The overall rate of self-reported non-adherence (CD: 20.9%, UC: 20.6%) and CAM (CD: 31.7%, UC: 30.9%) use did not differ between Crohn's disease (CD) and ulcerative colitis (UC). The most common causes of non-adherence were: forgetfulness (47.8%), too many/unnecessary pills (39.7%), being afraid of side effects (27.9%) and too frequent dosing. Most common forms of CAM were herbal tea (47.3%), homeopathy (14.6%), special diet (12.2%), and acupuncture (5.8%). In CD, disease duration, date of last follow-up visit, educational level and previous surgeries were predicting factors for non-adherence. Alternative medicine use was associated in both diseases with younger age, higher educational level, and immunosuppressant use. In addition, CAM use in UC was more common in females and in patients with supportive psychiatric/psychological therapy. Conclusions: Non-adherence and CAM use is common in patients with IBD. Special attention should be paid to explore the identified predictive factors during follow-up visits to improve adherence to therapy and improving patient-doctor relationship.

Original languageEnglish
Pages (from-to)283-290
Number of pages8
JournalJournal of Crohn's and Colitis
Volume4
Issue number3
DOIs
Publication statusPublished - Sep 1 2010

Keywords

  • Adherence
  • CD
  • Complementary medicine
  • IBD
  • UC

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Association of adherence to therapy and complementary and alternative medicine use with demographic factors and disease phenotype in patients with inflammatory bowel disease'. Together they form a unique fingerprint.

  • Cite this