Association between restless legs syndrome and depression in patients with chronic kidney disease

A. Szentkirályi, M. Molnár, Maria Eszter Czira, Gyorgy Deak, Anett Virag Lindner, L. Szeifert, Peter Torzsa, Eszter Panna Vamos, Rezso Zoller, I. Mucsi, M. Novák

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Restless legs syndrome (RLS) is reportedly associated with depression. This association may be mediated by both sleep-dependent and sleep-independent mechanisms. Here we analyze the association between RLS and depressive symptoms in patients with chronic kidney disease (CKD). We also assessed whether the relationship is independent of insomnia. In a cross-sectional study, socio-demographic parameters, laboratory data, and medical history were collected from 788 kidney transplant patients and 161 dialyzed patients. Insomnia, depression, and the presence of RLS symptoms were assessed with standard questionnaires. Patients with probable RLS had a higher prevalence of depressive symptoms than those without RLS (56% vs. 22% with vs. without RLS, respectively; P

Original languageEnglish
Pages (from-to)173-180
Number of pages8
JournalJournal of Psychosomatic Research
Volume67
Issue number2
DOIs
Publication statusPublished - Aug 2009

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Restless Legs Syndrome
Chronic Renal Insufficiency
Depression
Sleep Initiation and Maintenance Disorders
Sleep
Cross-Sectional Studies
Demography
Transplants
Kidney

Keywords

  • Chronic kidney disease
  • Depression
  • Dialysis
  • Insomnia
  • Kidney transplantation
  • Restless legs syndrome

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Association between restless legs syndrome and depression in patients with chronic kidney disease. / Szentkirályi, A.; Molnár, M.; Czira, Maria Eszter; Deak, Gyorgy; Lindner, Anett Virag; Szeifert, L.; Torzsa, Peter; Vamos, Eszter Panna; Zoller, Rezso; Mucsi, I.; Novák, M.

In: Journal of Psychosomatic Research, Vol. 67, No. 2, 08.2009, p. 173-180.

Research output: Contribution to journalArticle

Szentkirályi, A. ; Molnár, M. ; Czira, Maria Eszter ; Deak, Gyorgy ; Lindner, Anett Virag ; Szeifert, L. ; Torzsa, Peter ; Vamos, Eszter Panna ; Zoller, Rezso ; Mucsi, I. ; Novák, M. / Association between restless legs syndrome and depression in patients with chronic kidney disease. In: Journal of Psychosomatic Research. 2009 ; Vol. 67, No. 2. pp. 173-180.
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