Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery

M. Kertai, Eric Boersma, Cynthia M. Westerhout, Ron Van Domburg, Jan Klein, Jeroen J. Bax, Hero Van Urk, Don Poldermans

Research output: Contribution to journalArticle

179 Citations (Scopus)

Abstract

Purpose: To assess the potential long-term beneficial effects of statin use after successful abdominal aortic surgery. Methods: Between 1991 and 2001, 570 patients underwent abdominal aortic aneurysm repair at the Erasmus Medical Center. Of the 519 patients (91%) who survived surgery beyond 30 days, 510 (98%) were followed for a median of 4.7 years (interquartile range, 2.7 to 7.3 years). These patients were evaluated for use of statins and beta-blockers, and for clinical risk factors (e.g., advanced age; prior myocardial infarction; diabetes mellitus; renal dysfunction; chronic pulmonary disease; history of heart failure, stroke, or angina), and their association with all-cause and cardiovascular mortality. Results: A total of 205 patients (40%) died during follow-up; 140 due to cardiovascular causes. The incidence of all-cause (18% [27/154] vs. 50% [178/356], P

Original languageEnglish
Pages (from-to)96-103
Number of pages8
JournalThe American Journal of Medicine
Volume116
Issue number2
DOIs
Publication statusPublished - Jan 15 2004

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Abdominal Aortic Aneurysm
Mortality
Lung Diseases
Diabetes Mellitus
Chronic Disease
Heart Failure
Stroke
Myocardial Infarction
Kidney
Incidence

Keywords

  • Abdominal aortic aneurysm
  • Mortality
  • Statins

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery. / Kertai, M.; Boersma, Eric; Westerhout, Cynthia M.; Van Domburg, Ron; Klein, Jan; Bax, Jeroen J.; Van Urk, Hero; Poldermans, Don.

In: The American Journal of Medicine, Vol. 116, No. 2, 15.01.2004, p. 96-103.

Research output: Contribution to journalArticle

Kertai, M, Boersma, E, Westerhout, CM, Van Domburg, R, Klein, J, Bax, JJ, Van Urk, H & Poldermans, D 2004, 'Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery', The American Journal of Medicine, vol. 116, no. 2, pp. 96-103. https://doi.org/10.1016/j.amjmed.2003.08.029
Kertai, M. ; Boersma, Eric ; Westerhout, Cynthia M. ; Van Domburg, Ron ; Klein, Jan ; Bax, Jeroen J. ; Van Urk, Hero ; Poldermans, Don. / Association between long-term statin use and mortality after successful abdominal aortic aneurysm surgery. In: The American Journal of Medicine. 2004 ; Vol. 116, No. 2. pp. 96-103.
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