Association between bronchial asthma in pregnancy and shorter gestational age in a population-based study

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20 Citations (Scopus)

Abstract

Objective. To study the association between bronchial asthma during pregnancy and gestational age/birth weight, and also preterm birth and low birth weight. Method. In the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996, controls without congenital abnormalities were analysed. Results. Of 38,151 newborn infants, 757 (2.0%) had mothers with bronchial asthma during pregnancy, 88% were medically recorded prospectively. Mothers with bronchial asthma in pregnancy had 0.6 week shorter gestational age and a higher proportion of preterm births (14.1% vs. 9.1%). These findings were reflected with a lower mean birth weight (3,102 vs. 3,279 gram) and higher proportion of low birth weight newborns (9.0% vs. 5.6%). Conclusion. The old fashioned anti-asthmatic drugs were not able to prevent the bronchial asthma-related preterm birth, thus there is an urgent need to use modern inhaled therapies.

Original languageEnglish
Pages (from-to)107-112
Number of pages6
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume18
Issue number2
DOIs
Publication statusPublished - Aug 2005

Fingerprint

Gestational Age
Premature Birth
Asthma
Pregnancy
Low Birth Weight Infant
Birth Weight
Population
Mothers
Newborn Infant
Anti-Asthmatic Agents
Therapeutics

Keywords

  • Birth weight
  • Bronchial asthma
  • Gestational age
  • Preterm birth

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

Cite this

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title = "Association between bronchial asthma in pregnancy and shorter gestational age in a population-based study",
abstract = "Objective. To study the association between bronchial asthma during pregnancy and gestational age/birth weight, and also preterm birth and low birth weight. Method. In the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996, controls without congenital abnormalities were analysed. Results. Of 38,151 newborn infants, 757 (2.0{\%}) had mothers with bronchial asthma during pregnancy, 88{\%} were medically recorded prospectively. Mothers with bronchial asthma in pregnancy had 0.6 week shorter gestational age and a higher proportion of preterm births (14.1{\%} vs. 9.1{\%}). These findings were reflected with a lower mean birth weight (3,102 vs. 3,279 gram) and higher proportion of low birth weight newborns (9.0{\%} vs. 5.6{\%}). Conclusion. The old fashioned anti-asthmatic drugs were not able to prevent the bronchial asthma-related preterm birth, thus there is an urgent need to use modern inhaled therapies.",
keywords = "Birth weight, Bronchial asthma, Gestational age, Preterm birth",
author = "N. {\'A}cs and E. Puh{\'o} and F. B{\'a}nhidy and E. Czeizel",
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T1 - Association between bronchial asthma in pregnancy and shorter gestational age in a population-based study

AU - Ács, N.

AU - Puhó, E.

AU - Bánhidy, F.

AU - Czeizel, E.

PY - 2005/8

Y1 - 2005/8

N2 - Objective. To study the association between bronchial asthma during pregnancy and gestational age/birth weight, and also preterm birth and low birth weight. Method. In the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996, controls without congenital abnormalities were analysed. Results. Of 38,151 newborn infants, 757 (2.0%) had mothers with bronchial asthma during pregnancy, 88% were medically recorded prospectively. Mothers with bronchial asthma in pregnancy had 0.6 week shorter gestational age and a higher proportion of preterm births (14.1% vs. 9.1%). These findings were reflected with a lower mean birth weight (3,102 vs. 3,279 gram) and higher proportion of low birth weight newborns (9.0% vs. 5.6%). Conclusion. The old fashioned anti-asthmatic drugs were not able to prevent the bronchial asthma-related preterm birth, thus there is an urgent need to use modern inhaled therapies.

AB - Objective. To study the association between bronchial asthma during pregnancy and gestational age/birth weight, and also preterm birth and low birth weight. Method. In the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996, controls without congenital abnormalities were analysed. Results. Of 38,151 newborn infants, 757 (2.0%) had mothers with bronchial asthma during pregnancy, 88% were medically recorded prospectively. Mothers with bronchial asthma in pregnancy had 0.6 week shorter gestational age and a higher proportion of preterm births (14.1% vs. 9.1%). These findings were reflected with a lower mean birth weight (3,102 vs. 3,279 gram) and higher proportion of low birth weight newborns (9.0% vs. 5.6%). Conclusion. The old fashioned anti-asthmatic drugs were not able to prevent the bronchial asthma-related preterm birth, thus there is an urgent need to use modern inhaled therapies.

KW - Birth weight

KW - Bronchial asthma

KW - Gestational age

KW - Preterm birth

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