INTRODUCTION - Transvaginal color Doppler sonography provides the possibility to study pelvic tumor vascularity in benign and malignant pathologies. PATIENTS AND METHOD - The assessment of uterine blood flow characteristics in endometrial cancer and the evaluation of the influence of myometrial invasion and cancer grading for uterine vascularity were studied. Transvaginal color Doppler was used in 52 women with endometrial cancer and in 51 asymptomatic postmenopausal women as a control group. RESULTS - Endometrial blood flow was absent in the normal postmenopausal group on the level of the sensitivity of our equipment. In 45 (92%) of the 49 postmenopausal endometrial cancer patiens abnormal, turbulent blood flow was found with low impedance (RI: 0.39±0.08; PI: 0.51 ± 0.14) within the endometrial echo or very close to it. Impedance indices in the main uterine arteries were significantly (p<0,005) lower in women with endometrial cancer (RI: 0.78±0.10; PI: 1.69±0.56) than in normal postmenopausal woman (RI: 0.93±0.08; PI: 3.06±1.04). Uterine blood flow was not modified by the cancer grading. There was not any difference in impedance indices of the uterine arteries compared myometrial invasion of <50% and of >50%. CONCLUSION - Endometrial cancer may cause characteristic vascular and blood flow changes in the uterine circulatory system that can be assessed by transvaginal color and pulsed Doppler.
|Number of pages||8|
|Journal||Lege Artis Medicinae|
|Publication status||Published - Dec 1 1996|
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