The innocuousness and activity of the gE-TK-Belmer strain of ADV was evaluated in 5 days old piglets which were vaccinated by intranasal route. This vaccine strain proved to be innocuous and no adverse side effects were observed in the vaccinated group. The percent mean daily weight gain up to the time of challenge infection (62 dpv) was similar in the vaccinated (18.29%) and in the control pigs (17.42%). The vaccinated pigs remained protected whereas 80% of the control animals died after the experimental infection. Only in 5% of the nasal swabbs from the vaccinated pigs ADV was detected whereas in the control group the ratio was 79%. Both the strain and the route used proved to be highly active to prevent AD.
|Publication status||Published - Jan 1 1997|
- Belmer strain
- intranasal route
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