Assessment of target-organ damage in adolescent white-coat and sustained hypertensives

D. Páll, Mária Juhász, Szabolcs Lengyel, Csilla Molnár, G. Paragh, B. Fülesdi, E. Katona

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Aims and scope: The aim of the present study was to assess whether a difference exists between intima-media thickness and the left ventricular mass index in healthy nonhypertensive, white-coat hypertensive and sustained hypertensive adolescents. Patients and methods: Fifty-nine normotensive and 120 hypertensive adolescents were enrolled in our study. Hypertensive patients were classified into white-coat hypertension (WCH) and sustained hypertension groups based on 24-h ambulatory blood pressure measurements. Both normotensive and hypertensive individuals underwent routine laboratory tests, intima-media thickness measurements on the common carotid arteries and transthoracic echocardiography to measure the left ventricular mass index (LVMI). RESULTS: Intima-media thickness was higher both in WCH and sustained hypertension compared with healthy normotensive individuals (controls: 0.048 ± 0.01 cm, WCH: 0.056 ± 0.01 cm, sustained hypertension: 0.054 ± 0.012 cm, both P <0.001 compared with controls, nonsignificant difference between the two hypertensive groups). There was no difference between the LVMI of control individuals and WCH (LVMI: 35.5 ± 10.3 g/m and 37.7 ± 11.2 g/m respectively, P = 0.87). LVMI in sustained hypertension group (LVMI: 44.1 ± 14.1 g/m) was significantly higher both compared with WCH (P <0.05), and healthy adolescents (P <0.001). Conclusion: Target-organ damage develops in a stepwise fashion in adolescent hypertension. An increased intima-media thickness can be demonstrated not only in the sustained but also in the white-coat form of adolescent hypertension.

Original languageEnglish
Pages (from-to)2139-2144
Number of pages6
JournalJournal of Hypertension
Volume28
Issue number10
DOIs
Publication statusPublished - Oct 2010

Fingerprint

White Coat Hypertension
Hypertension
Common Carotid Artery
Echocardiography
Blood Pressure

Keywords

  • adolescent
  • target-organ damage
  • white-coat hypertension

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Assessment of target-organ damage in adolescent white-coat and sustained hypertensives. / Páll, D.; Juhász, Mária; Lengyel, Szabolcs; Molnár, Csilla; Paragh, G.; Fülesdi, B.; Katona, E.

In: Journal of Hypertension, Vol. 28, No. 10, 10.2010, p. 2139-2144.

Research output: Contribution to journalArticle

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AU - Katona, E.

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