Psoriasisban szenvedo betegek életminoségének vizsgálata Magyarországon

Translated title of the contribution: Assessment of health-related quality of life in psoriasis patients in Hungary

Poór Adrienn Katalin, Sárdy Miklós, Cserni Tamás, Brodszky Valentin, Holló Péter, L. Gulácsi, E. Remenyik, Szegedi Andrea, Rencz Fanni, Péntek Márta

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Introduction: The health status and health-related quality of life (HRQoL) of patients with psoriasis in Hungary are understudied. Aim: To assess HRQoL in psoriasis patients, to compare HRQoL of psoriasis patients to that of the general public in Hungary and to identify predictors of HRQoL. Method: Between 2012 and 2016, two cross-sectional surveys were carried out among psoriasis patients at two academic dermatology departments. HRQoL was assessed by EQ-5D-3L, EQ Visual Analogue Scale (EQ VAS) and Dermatology Life Quality Index (DLQI). Predictors of HRQoL were analysed by multivariate linear regression. Results: 434 patients were enrolled (mean age 49 years, 65% male, 81% moderate-to-severe psoriasis, 43% treated with biologics). Mean EQ-5D-3L, EQ VAS and DLQI scores were 0.74 ± 0.28, 69.06 ± 20.98 and 6.78 ± 7.38, respectively. Overall, 54%, 43%, 40%, 32% and 15% of patients indicated at least some problems in pain/discomfort, anxiety/depression, mobility, usual activities and self-care. EQ-5D-3L index scores in patients were lower compared to the age- and gender-matched general population in Hungary. The difference was statistically significant for the age groups 25-34 and 45-64 in males, and 18-64 in females (p<0.05). Female gender (p = 0.042), psoriatic arthritis (p<0.001) and palmoplantar psoriasis (p = 0.031) were associated with lower EQ-5D-3L index scores. On the contrary, employed and highly educated patients reported higher EQ-5D-3L index scores (p<0.001). Conclusions: We were the first to assess HRQoL in psoriasis patients by using EQ-5D questionnaire in Hungary, and more broadly in Central and Eastern Europe. Our findings are useful for cost-effectiveness modelling of psoriasis treatments and decision-making in healthcare.

Original languageHungarian
Pages (from-to)837-846
Number of pages10
JournalOrvosi Hetilap
Volume159
Issue number21
DOIs
Publication statusPublished - May 1 2018

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Hungary
Psoriasis
Quality of Life
Dermatology
Visual Analog Scale
Eastern Europe
Psoriatic Arthritis
Self Care
Biological Products
Health Status
Cost-Benefit Analysis
Linear Models
Decision Making
Anxiety
Age Groups
Cross-Sectional Studies
Depression
Delivery of Health Care
Pain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Katalin, P. A., Miklós, S., Tamás, C., Valentin, B., Péter, H., Gulácsi, L., ... Márta, P. (2018). Psoriasisban szenvedo betegek életminoségének vizsgálata Magyarországon. Orvosi Hetilap, 159(21), 837-846. https://doi.org/10.1556/650.2018.31061

Psoriasisban szenvedo betegek életminoségének vizsgálata Magyarországon. / Katalin, Poór Adrienn; Miklós, Sárdy; Tamás, Cserni; Valentin, Brodszky; Péter, Holló; Gulácsi, L.; Remenyik, E.; Andrea, Szegedi; Fanni, Rencz; Márta, Péntek.

In: Orvosi Hetilap, Vol. 159, No. 21, 01.05.2018, p. 837-846.

Research output: Contribution to journalArticle

Katalin, PA, Miklós, S, Tamás, C, Valentin, B, Péter, H, Gulácsi, L, Remenyik, E, Andrea, S, Fanni, R & Márta, P 2018, 'Psoriasisban szenvedo betegek életminoségének vizsgálata Magyarországon', Orvosi Hetilap, vol. 159, no. 21, pp. 837-846. https://doi.org/10.1556/650.2018.31061
Katalin, Poór Adrienn ; Miklós, Sárdy ; Tamás, Cserni ; Valentin, Brodszky ; Péter, Holló ; Gulácsi, L. ; Remenyik, E. ; Andrea, Szegedi ; Fanni, Rencz ; Márta, Péntek. / Psoriasisban szenvedo betegek életminoségének vizsgálata Magyarországon. In: Orvosi Hetilap. 2018 ; Vol. 159, No. 21. pp. 837-846.
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abstract = "Introduction: The health status and health-related quality of life (HRQoL) of patients with psoriasis in Hungary are understudied. Aim: To assess HRQoL in psoriasis patients, to compare HRQoL of psoriasis patients to that of the general public in Hungary and to identify predictors of HRQoL. Method: Between 2012 and 2016, two cross-sectional surveys were carried out among psoriasis patients at two academic dermatology departments. HRQoL was assessed by EQ-5D-3L, EQ Visual Analogue Scale (EQ VAS) and Dermatology Life Quality Index (DLQI). Predictors of HRQoL were analysed by multivariate linear regression. Results: 434 patients were enrolled (mean age 49 years, 65{\%} male, 81{\%} moderate-to-severe psoriasis, 43{\%} treated with biologics). Mean EQ-5D-3L, EQ VAS and DLQI scores were 0.74 ± 0.28, 69.06 ± 20.98 and 6.78 ± 7.38, respectively. Overall, 54{\%}, 43{\%}, 40{\%}, 32{\%} and 15{\%} of patients indicated at least some problems in pain/discomfort, anxiety/depression, mobility, usual activities and self-care. EQ-5D-3L index scores in patients were lower compared to the age- and gender-matched general population in Hungary. The difference was statistically significant for the age groups 25-34 and 45-64 in males, and 18-64 in females (p<0.05). Female gender (p = 0.042), psoriatic arthritis (p<0.001) and palmoplantar psoriasis (p = 0.031) were associated with lower EQ-5D-3L index scores. On the contrary, employed and highly educated patients reported higher EQ-5D-3L index scores (p<0.001). Conclusions: We were the first to assess HRQoL in psoriasis patients by using EQ-5D questionnaire in Hungary, and more broadly in Central and Eastern Europe. Our findings are useful for cost-effectiveness modelling of psoriasis treatments and decision-making in healthcare.",
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AU - Tamás, Cserni

AU - Valentin, Brodszky

AU - Péter, Holló

AU - Gulácsi, L.

AU - Remenyik, E.

AU - Andrea, Szegedi

AU - Fanni, Rencz

AU - Márta, Péntek

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N2 - Introduction: The health status and health-related quality of life (HRQoL) of patients with psoriasis in Hungary are understudied. Aim: To assess HRQoL in psoriasis patients, to compare HRQoL of psoriasis patients to that of the general public in Hungary and to identify predictors of HRQoL. Method: Between 2012 and 2016, two cross-sectional surveys were carried out among psoriasis patients at two academic dermatology departments. HRQoL was assessed by EQ-5D-3L, EQ Visual Analogue Scale (EQ VAS) and Dermatology Life Quality Index (DLQI). Predictors of HRQoL were analysed by multivariate linear regression. Results: 434 patients were enrolled (mean age 49 years, 65% male, 81% moderate-to-severe psoriasis, 43% treated with biologics). Mean EQ-5D-3L, EQ VAS and DLQI scores were 0.74 ± 0.28, 69.06 ± 20.98 and 6.78 ± 7.38, respectively. Overall, 54%, 43%, 40%, 32% and 15% of patients indicated at least some problems in pain/discomfort, anxiety/depression, mobility, usual activities and self-care. EQ-5D-3L index scores in patients were lower compared to the age- and gender-matched general population in Hungary. The difference was statistically significant for the age groups 25-34 and 45-64 in males, and 18-64 in females (p<0.05). Female gender (p = 0.042), psoriatic arthritis (p<0.001) and palmoplantar psoriasis (p = 0.031) were associated with lower EQ-5D-3L index scores. On the contrary, employed and highly educated patients reported higher EQ-5D-3L index scores (p<0.001). Conclusions: We were the first to assess HRQoL in psoriasis patients by using EQ-5D questionnaire in Hungary, and more broadly in Central and Eastern Europe. Our findings are useful for cost-effectiveness modelling of psoriasis treatments and decision-making in healthcare.

AB - Introduction: The health status and health-related quality of life (HRQoL) of patients with psoriasis in Hungary are understudied. Aim: To assess HRQoL in psoriasis patients, to compare HRQoL of psoriasis patients to that of the general public in Hungary and to identify predictors of HRQoL. Method: Between 2012 and 2016, two cross-sectional surveys were carried out among psoriasis patients at two academic dermatology departments. HRQoL was assessed by EQ-5D-3L, EQ Visual Analogue Scale (EQ VAS) and Dermatology Life Quality Index (DLQI). Predictors of HRQoL were analysed by multivariate linear regression. Results: 434 patients were enrolled (mean age 49 years, 65% male, 81% moderate-to-severe psoriasis, 43% treated with biologics). Mean EQ-5D-3L, EQ VAS and DLQI scores were 0.74 ± 0.28, 69.06 ± 20.98 and 6.78 ± 7.38, respectively. Overall, 54%, 43%, 40%, 32% and 15% of patients indicated at least some problems in pain/discomfort, anxiety/depression, mobility, usual activities and self-care. EQ-5D-3L index scores in patients were lower compared to the age- and gender-matched general population in Hungary. The difference was statistically significant for the age groups 25-34 and 45-64 in males, and 18-64 in females (p<0.05). Female gender (p = 0.042), psoriatic arthritis (p<0.001) and palmoplantar psoriasis (p = 0.031) were associated with lower EQ-5D-3L index scores. On the contrary, employed and highly educated patients reported higher EQ-5D-3L index scores (p<0.001). Conclusions: We were the first to assess HRQoL in psoriasis patients by using EQ-5D questionnaire in Hungary, and more broadly in Central and Eastern Europe. Our findings are useful for cost-effectiveness modelling of psoriasis treatments and decision-making in healthcare.

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KW - Health-related quality of life

KW - Hungary

KW - Psoriasis

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