The aim of this chapter is to provide a comprehensive review of the interrelationships between stress and ascorbate metabolism. First, the effect of stress on ascorbate levels and the beneficial effects of ascorbate supplementation during stress conditions are surveyed. As a background of these events, the synthesis and the breakdown of ascorbate as well as its recycling are also treated. Regulation of ascorbate metabolism and its alterations under stress conditions are discussed in detail. The importance of hepatocellular and interorgan cycles with the participation of ascorbate in economical ascorbate handling is underlined in both ascorbate synthesizing and nonsynthesizing species.
|Number of pages||12|
|Journal||Annals of the New York Academy of Sciences|
|Publication status||Published - Jan 1 1998|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- History and Philosophy of Science