Arsenic exposure in Hungary, Romania and Slovakia

Anna Lena Lindberg, Walter Goessler, Eugen Gurzau, Kvetoslava Koppova, P. Rudnai, Rajiv Kumar, Tony Fletcher, Giovanni Leonardi, Katarina Slotova, Emilia Gheorghiu, Marie Vahter

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

Inorganic arsenic is a potent human carcinogen and toxicant which people are exposed to mainly via drinking water and food. The objective of the present study was to assess current exposure to arsenic via drinking water in three European countries. For this purpose, 520 individuals from four Hungarian, two Slovakian and two Romanian countries were investigated by measuring inorganic arsenic and methylated arsenic metabolites in urine by high performance liquid chromatography with hydride generation and inductively coupled plasma mass spectrometry. Arsenic in drinking water was determined by atomic absorption spectrometry. Significantly higher concentrations of arsenic were found in both the water and the urine samples from the Hungarian counties (median: 11 and 15 μg dm-3, respectively; p <0.001) than from the Slovakian (median: 0.94 and 4.5 μg dm-3, respectively) and Romanian (median: 0.70 and 2.1 μg dm-3, respectively) counties. A significant correlation was seen between arsenic in water and arsenic in urine (R 2 = 0.46). At low water arsenic concentrations, the relative amount of dimethylarsinic acid (DMA) in urine was increased, indicating exposure via food. Also, high body mass index was associated with higher concentrations of arsenic in urine (p = 0.03), mostly in the form of DMA. Smokers had significantly higher urinary arsenic concentrations than non-smokers (p = 0.03). In conclusion, elevated arsenic exposure via drinking water was prevalent in some of the counties. Exposure to arsenic from food, mainly as DMA, and cigarette smoke, mainly as inorganic arsenic, are major determinants of arsenic exposure at very low concentrations of arsenic in drinking water.

Original languageEnglish
Pages (from-to)203-208
Number of pages6
JournalJournal of Environmental Monitoring
Volume8
Issue number1
DOIs
Publication statusPublished - Jan 2006

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Romania
Slovakia
Hungary
Arsenic
arsenic
Drinking Water
urine
Cacodylic Acid
drinking water
Urine
exposure
Food
food
Water
acid
Inductively coupled plasma mass spectrometry
Atomic absorption spectrometry
High performance liquid chromatography
carcinogen
Metabolites

ASJC Scopus subject areas

  • Environmental Science(all)
  • Environmental Chemistry

Cite this

Lindberg, A. L., Goessler, W., Gurzau, E., Koppova, K., Rudnai, P., Kumar, R., ... Vahter, M. (2006). Arsenic exposure in Hungary, Romania and Slovakia. Journal of Environmental Monitoring, 8(1), 203-208. https://doi.org/10.1039/b513206a

Arsenic exposure in Hungary, Romania and Slovakia. / Lindberg, Anna Lena; Goessler, Walter; Gurzau, Eugen; Koppova, Kvetoslava; Rudnai, P.; Kumar, Rajiv; Fletcher, Tony; Leonardi, Giovanni; Slotova, Katarina; Gheorghiu, Emilia; Vahter, Marie.

In: Journal of Environmental Monitoring, Vol. 8, No. 1, 01.2006, p. 203-208.

Research output: Contribution to journalArticle

Lindberg, AL, Goessler, W, Gurzau, E, Koppova, K, Rudnai, P, Kumar, R, Fletcher, T, Leonardi, G, Slotova, K, Gheorghiu, E & Vahter, M 2006, 'Arsenic exposure in Hungary, Romania and Slovakia', Journal of Environmental Monitoring, vol. 8, no. 1, pp. 203-208. https://doi.org/10.1039/b513206a
Lindberg AL, Goessler W, Gurzau E, Koppova K, Rudnai P, Kumar R et al. Arsenic exposure in Hungary, Romania and Slovakia. Journal of Environmental Monitoring. 2006 Jan;8(1):203-208. https://doi.org/10.1039/b513206a
Lindberg, Anna Lena ; Goessler, Walter ; Gurzau, Eugen ; Koppova, Kvetoslava ; Rudnai, P. ; Kumar, Rajiv ; Fletcher, Tony ; Leonardi, Giovanni ; Slotova, Katarina ; Gheorghiu, Emilia ; Vahter, Marie. / Arsenic exposure in Hungary, Romania and Slovakia. In: Journal of Environmental Monitoring. 2006 ; Vol. 8, No. 1. pp. 203-208.
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