Are Alzheimer's disease patients able to learn visual prototypes?

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Recently, controversial results emerged regarding visual prototype learning in Alzheimer's disease (AD). The aim of this study was to elucidate this issue in a larger population of AD patients. The AD patients (N=72) and age-matched healthy control subjects (N=25) learned to recognize and to categorize visual dot patterns. In comparison with the control subjects, the AD patients as a group showed dysfunctions in the recognition task, whereas categorization was relatively spared in their case. Recognition was impaired in patients with mild AD (Mini-Mental score: 18-23) and moderate AD (Mini-Mental score<18), whereas categorization was impaired only in patients with moderate AD. These results suggest that while the medio-temporal/diencephalic explicit memory system is markedly affected even in early AD, the sensory neocortical areas mediating implicit category learning display a sufficient degree of functional capacity until later stages of the disease.

Original languageEnglish
Pages (from-to)1218-1223
Number of pages6
JournalNeuropsychologia
Volume39
Issue number11
DOIs
Publication statusPublished - Sep 11 2001

Keywords

  • Alzheimer's disease
  • Category learning
  • Explicit memory
  • Implicit memory
  • Recognition
  • Sensory neocortex

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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