### Abstract

We extrapolate from the exact master equations of epidemic dynamics on fully connected graphs to non-fully connected by keeping the size of the state space N + 1, where N is the number of nodes in the graph. This gives rise to a system of approximate ODEs (ordinary differential equations) where the challenge is to compute/approximate analytically the transmission rates. We show that this is possible for graphs with arbitrary degree distributions built according to the configuration model. Numerical tests confirm that: (a) the agreement of the approximate ODEs system with simulation is excellent and (b) that the approach remains valid for clustered graphs with the analytical calculations of the transmission rates still pending. The marked reduction in state space gives good results, and where the transmission rates can be analytically approximated, the model provides a strong alternative approximate model that agrees well with simulation. Given that the transmission rates encompass information both about the dynamics and graph properties, the specific shape of the curve, defined by the transmission rate versus the number of infected nodes, can provide a new and different measure of network structure, and the model could serve as a link between inferring network structure from prevalence or incidence data.

Original language | English |
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Pages (from-to) | 43-57 |

Number of pages | 15 |

Journal | Mathematical Modelling of Natural Phenomena |

Volume | 9 |

Issue number | 2 |

DOIs | |

Publication status | Published - 2014 |

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### Keywords

- Network process
- ODE approximation
- SIS epidemic

### ASJC Scopus subject areas

- Modelling and Simulation
- Applied Mathematics

### Cite this

*Mathematical Modelling of Natural Phenomena*,

*9*(2), 43-57. https://doi.org/10.1051/mmnp/20149203