Appropriate sampling times for growth hormone (GH) measurement during insulin tolerance testing (ITT) in children.

A. Muzsnai, J. Sólyom, I. Ilyés, J. Kovács, E. Sólyom, T. Niederland, F. Péter

Research output: Contribution to journalArticle

Abstract

Background: The Pfizer International Metabolic Database (KIMS), a large pharmacoepidemiologic database for adults with growth hormone deficiency (GHD), was recently analyzed to determine which tests are in use to assess GHD and how well they correlate. At the time of this analysis, a total of 15,724 tests had been reported to KIMS. The most frequently used is the insulin tolerance test (ITT), followed in order by the arginine stimulation test (AST), the glucagon stimulation test (GST) and the GH-releasing hormone+arginine (GHRH+arg) test. The ITT correlated with both the AST and the GST, but not with the GHRH+arg. Conclusions:For the AST and GST, use of a diagnostic threshold of 3 mug/l does not attenuate the effects of severe GHD. Copyright (c) 2007 S. Karger AG, Basel.

Original languageEnglish
Pages (from-to)205-206
Number of pages2
JournalHormone research
Volume68 Suppl 5
DOIs
Publication statusPublished - 2007

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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