The tert-amino effect has been shown to be conveniently applicable to the synthesis of novel spirocyclic ring systems containing a pyridodiazine skeleton. Kinetic and X-ray measurements were also carried out to explain the effect of substituents on the rearrangement reaction. An efficient pathway involving an intramolecular 1,3-dipolar cycloaddition led to a structurally related angularly annelated isoxazolo pyridopyridazine. (C) 2000 Elsevier Science B.V.
- Pyridodiazines X-ray crystal structures
- Tert-Amino effect
ASJC Scopus subject areas
- Condensed Matter Physics
- Physical and Theoretical Chemistry