Applications of tert-amino effect and a nitrone-olefin 1,3-dipolar cycloaddition reaction: Synthesis of novel angularly annelated diazino heterocycles

A. Schwartz, G. Beke, Z. Kovári, Z. Böcskey, Ö Farkas, P. Mátyus

Research output: Contribution to journalArticle

23 Citations (Scopus)


The tert-amino effect has been shown to be conveniently applicable to the synthesis of novel spirocyclic ring systems containing a pyridodiazine skeleton. Kinetic and X-ray measurements were also carried out to explain the effect of substituents on the rearrangement reaction. An efficient pathway involving an intramolecular 1,3-dipolar cycloaddition led to a structurally related angularly annelated isoxazolo pyridopyridazine. (C) 2000 Elsevier Science B.V.

Original languageEnglish
Pages (from-to)49-57
Number of pages9
JournalJournal of Molecular Structure: THEOCHEM
Issue number1-3
Publication statusPublished - Aug 25 2000



  • Nitrones
  • Pyridazines
  • Pyridodiazines X-ray crystal structures
  • Tert-Amino effect

ASJC Scopus subject areas

  • Biochemistry
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

Cite this